Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

Serena Zanelli; Davide Agnoletti; Jordi Alastruey; John Allen; Elisabetta Bianchini; Vasiliki Bikia; Pierre Boutouyrie; Rosa Maria Bruno; Rachel Climie; Djeldjli Djamaleddine; Eugenia Gkaliagkousi; Alessandro Giudici; Kristina Gopcevic; Andrea Grillo; Andrea Guala; Bernhard Hametner; Jayaraj Joseph; Parmis Karimpour; Vimarsha Kodithuwakku; Panayiotis A Kyriacou; Antonios Lazaridis; Mai Tone Lonnebakken; Maria Raffaella Martina; Christopher Clemens Mayer; P M Nabeel; Petras Navickas; Janos Nemcsik; Stefan Orter; Chloe Park; Telmo Pereira; Giacomo Pucci; Ana Belen Amado Rey; Paolo Salvi; Ana Carolina Gonçalves Seabra; Ute Seeland; Thomas van Sloten; Bart Spronck; Gerard Stansby; Indra Steens; Thomas Stieglitz; Isabella Tan; Dave Veerasingam; Siegfried Wassertheurer; Thomas Weber; Berend E. Westerhof; Peter H. Charlton

doi:10.1088/1361-6579/ad548e

Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

Serena Zanelli, Davide Agnoletti, Jordi Alastruey, John Allen, Elisabetta Bianchini, Vasiliki Bikia, Pierre Boutouyrie, Rosa Maria Bruno, Rachel Climie, Djeldjli Djamaleddine, Eugenia Gkaliagkousi, Alessandro Giudici, Kristina Gopcevic, Andrea Grillo, Andrea Guala, Bernhard Hametner, Jayaraj Joseph, Parmis Karimpour, Vimarsha Kodithuwakku, Panayiotis A KyriacouAntonios Lazaridis, Mai Tone Lonnebakken, Maria Raffaella Martina, Christopher Clemens Mayer, P M Nabeel, Petras Navickas, Janos Nemcsik, Stefan Orter, Chloe Park, Telmo Pereira, Giacomo Pucci, Ana Belen Amado Rey, Paolo Salvi, Ana Carolina Gonçalves Seabra, Ute Seeland, Thomas van Sloten, Bart Spronck, Gerard Stansby, Indra Steens, Thomas Stieglitz, Isabella Tan, Dave Veerasingam, Siegfried Wassertheurer, Thomas Weber, Berend E. Westerhof, Peter H. Charlton

Centre for Intelligent Healthcare

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Abstract

Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

Original language	English
Pages (from-to)	(In-Press)
Journal	Physiological Measurement
Volume	(In-Press)
Early online date	5 Jun 2024
DOIs	https://doi.org/10.1088/1361-6579/ad548e
Publication status	E-pub ahead of print - 5 Jun 2024

Keywords

arterial stiffness
arteriosclerosis
atherosclerosis
blood pressure
cardiovascular
prevention
pulse wave velocity
risk assessment

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Zanelli, S., Agnoletti, D., Alastruey, J., Allen, J., Bianchini, E., Bikia, V., Boutouyrie, P., Bruno, R. M., Climie, R., Djamaleddine, D., Gkaliagkousi, E., Giudici, A., Gopcevic, K., Grillo, A., Guala, A., Hametner, B., Joseph, J., Karimpour, P., Kodithuwakku, V., ... Charlton, P. H. (2024). Developing technologies to assess vascular ageing: a roadmap from VascAgeNet. Physiological Measurement, (In-Press), (In-Press). Advance online publication. https://doi.org/10.1088/1361-6579/ad548e

Zanelli, S, Agnoletti, D, Alastruey, J, Allen, J, Bianchini, E, Bikia, V, Boutouyrie, P, Bruno, RM, Climie, R, Djamaleddine, D, Gkaliagkousi, E, Giudici, A, Gopcevic, K, Grillo, A, Guala, A, Hametner, B, Joseph, J, Karimpour, P, Kodithuwakku, V, Kyriacou, PA, Lazaridis, A, Lonnebakken, MT, Martina, MR, Mayer, CC, Nabeel, PM, Navickas, P, Nemcsik, J, Orter, S, Park, C, Pereira, T, Pucci, G, Rey, ABA, Salvi, P, Seabra, ACG, Seeland, U, van Sloten, T, Spronck, B, Stansby, G, Steens, I, Stieglitz, T, Tan, I, Veerasingam, D, Wassertheurer, S, Weber, T, Westerhof, BE & Charlton, PH 2024, 'Developing technologies to assess vascular ageing: a roadmap from VascAgeNet', Physiological Measurement, vol. (In-Press), pp. (In-Press). https://doi.org/10.1088/1361-6579/ad548e

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abstract = "Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.",

keywords = "arterial stiffness, arteriosclerosis, atherosclerosis, blood pressure, cardiovascular, prevention, pulse wave velocity, risk assessment",

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AU - Zanelli, Serena

AU - Agnoletti, Davide

AU - Alastruey, Jordi

AU - Allen, John

AU - Bianchini, Elisabetta

AU - Bikia, Vasiliki

AU - Boutouyrie, Pierre

AU - Bruno, Rosa Maria

AU - Climie, Rachel

AU - Djamaleddine, Djeldjli

AU - Gkaliagkousi, Eugenia

AU - Giudici, Alessandro

AU - Gopcevic, Kristina

AU - Grillo, Andrea

AU - Guala, Andrea

AU - Hametner, Bernhard

AU - Joseph, Jayaraj

AU - Karimpour, Parmis

AU - Kodithuwakku, Vimarsha

AU - Kyriacou, Panayiotis A

AU - Lazaridis, Antonios

AU - Lonnebakken, Mai Tone

AU - Martina, Maria Raffaella

AU - Mayer, Christopher Clemens

AU - Nabeel, P M

AU - Navickas, Petras

AU - Nemcsik, Janos

AU - Orter, Stefan

AU - Park, Chloe

AU - Pereira, Telmo

AU - Pucci, Giacomo

AU - Rey, Ana Belen Amado

AU - Salvi, Paolo

AU - Seabra, Ana Carolina Gonçalves

AU - Seeland, Ute

AU - van Sloten, Thomas

AU - Spronck, Bart

AU - Stansby, Gerard

AU - Steens, Indra

AU - Stieglitz, Thomas

AU - Tan, Isabella

AU - Veerasingam, Dave

AU - Wassertheurer, Siegfried

AU - Weber, Thomas

AU - Westerhof, Berend E.

AU - Charlton, Peter H.

PY - 2024/6/5

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N2 - Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

AB - Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

KW - arterial stiffness

KW - arteriosclerosis

KW - atherosclerosis

KW - blood pressure

KW - cardiovascular

KW - prevention

KW - pulse wave velocity

KW - risk assessment

U2 - 10.1088/1361-6579/ad548e

DO - 10.1088/1361-6579/ad548e

M3 - Article

SN - 0967-3334

VL - (In-Press)

SP - (In-Press)

JO - Physiological Measurement

JF - Physiological Measurement

ER -

Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

Abstract

Keywords

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