Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects

Zhiqing Chen; Lingna  Mao; Chengyu Liu; James R.  Blake; Dingchang Zheng

doi:10.1038/srep06685

Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects

Zhiqing Chen, Lingna Mao, Chengyu Liu, James R. Blake, Dingchang Zheng

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Abstract

This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial volume distensibility. In comparison with the normal subjects, after adjusting for pulse pressure, baPWV in the BRVO patients was significantly higher by 2.3 m/s (P , 0.01)
and arterial distensibility was significantly lower by 0.015% per mmHg (P , 0.01). No subject in the normal
group had an arterial distensibility lower than 0.04% per mmHg, in comparison with 67% (20/30) in the BRVO group. Arterial distensibility was significantly related to systolic and diastolic blood pressures (SBP and DBP) and ageing for both groups (all P , 0.05), but in the BRVO group, blood pressures and ageing had
more prominent effect on arterial volume distensibility. Peripheral arterial distensibility has been shown to be significantly lower in BRVO patients in comparison with normal subjects. The more prominent effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechanisms of the
interaction between higher blood pressures, ageing and BRVO disease.

Original language	English
Article number	6685
Number of pages	6
Journal	Scientific Reports
Volume	4
DOIs	https://doi.org/10.1038/srep06685
Publication status	Published - 24 Oct 2014
Externally published	Yes

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This work is licensed under a Creative Commons Attribution-NonCommercialNoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder
in order to reproduce the material. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-nd/4.0/

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Chen, Z., Mao, L., Liu, C., Blake, J. R., & Zheng, D. (2014). Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects. Scientific Reports, 4, [6685 ]. https://doi.org/10.1038/srep06685

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abstract = "This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial volume distensibility. In comparison with the normal subjects, after adjusting for pulse pressure, baPWV in the BRVO patients was significantly higher by 2.3 m/s (P , 0.01)and arterial distensibility was significantly lower by 0.015{\%} per mmHg (P , 0.01). No subject in the normalgroup had an arterial distensibility lower than 0.04{\%} per mmHg, in comparison with 67{\%} (20/30) in the BRVO group. Arterial distensibility was significantly related to systolic and diastolic blood pressures (SBP and DBP) and ageing for both groups (all P , 0.05), but in the BRVO group, blood pressures and ageing hadmore prominent effect on arterial volume distensibility. Peripheral arterial distensibility has been shown to be significantly lower in BRVO patients in comparison with normal subjects. The more prominent effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechanisms of theinteraction between higher blood pressures, ageing and BRVO disease.",

author = "Zhiqing Chen and Lingna Mao and Chengyu Liu and Blake, {James R.} and Dingchang Zheng",

note = "This work is licensed under a Creative Commons Attribution-NonCommercialNoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-nd/4.0/",

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N1 - This work is licensed under a Creative Commons Attribution-NonCommercialNoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-nd/4.0/

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N2 - This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial volume distensibility. In comparison with the normal subjects, after adjusting for pulse pressure, baPWV in the BRVO patients was significantly higher by 2.3 m/s (P , 0.01)and arterial distensibility was significantly lower by 0.015% per mmHg (P , 0.01). No subject in the normalgroup had an arterial distensibility lower than 0.04% per mmHg, in comparison with 67% (20/30) in the BRVO group. Arterial distensibility was significantly related to systolic and diastolic blood pressures (SBP and DBP) and ageing for both groups (all P , 0.05), but in the BRVO group, blood pressures and ageing hadmore prominent effect on arterial volume distensibility. Peripheral arterial distensibility has been shown to be significantly lower in BRVO patients in comparison with normal subjects. The more prominent effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechanisms of theinteraction between higher blood pressures, ageing and BRVO disease.

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