Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects

Zhiqing Chen, Lingna Mao, Chengyu Liu, James R. Blake, Dingchang Zheng

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Abstract

This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial volume distensibility. In comparison with the normal subjects, after adjusting for pulse pressure, baPWV in the BRVO patients was significantly higher by 2.3 m/s (P , 0.01)
and arterial distensibility was significantly lower by 0.015% per mmHg (P , 0.01). No subject in the normal
group had an arterial distensibility lower than 0.04% per mmHg, in comparison with 67% (20/30) in the BRVO group. Arterial distensibility was significantly related to systolic and diastolic blood pressures (SBP and DBP) and ageing for both groups (all P , 0.05), but in the BRVO group, blood pressures and ageing had
more prominent effect on arterial volume distensibility. Peripheral arterial distensibility has been shown to be significantly lower in BRVO patients in comparison with normal subjects. The more prominent effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechanisms of the
interaction between higher blood pressures, ageing and BRVO disease.
Original languageEnglish
Article number6685
Number of pages6
JournalScientific Reports
Volume4
DOIs
Publication statusPublished - 24 Oct 2014
Externally publishedYes

Bibliographical note

This work is licensed under a Creative Commons Attribution-NonCommercialNoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder
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