Dataset on Blood Flow and Instantaneous Wave-free Ratio in Normal and Stenosed Coronary Arteries

Haipeng Liu, Shanxing Ou, Panli Liu, Yuhang Xu, Yinglan Gong, Ling Xia, Xinyi Leng, Thomas Wai Hong Leung, Lin Shi, Dingchang Zheng

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    Instantaneous wave-free ratio (iFR) has been proposed as a hemodynamic parameter that can reliably reflect the blood flow in stenosed coronary arteries. Currently, there are few investigations on the quantitative analysis of iFR in the patients regarding the variation of microcirculatory resistance (MR). The data aim to provide geometric (cross-section area of branches) and hemodynamic (flow rate and iFR of branches) parameters of normal and stenosed coronary arteries derived from CFD simulation. The CFD simulation was performed on the three-dimensional artery models reconstructed from computed tomography (CT) images of four subjects. The hemodynamic parameters were obtained in six situations of MR to simulate coronary microvascular dysfunction (CMD). This dataset could be used as the reference to estimate the iFR and flow rate in patients with CMD and stenosis in coronary arteries. The geometric parameters could be used in the modelling of coronary arteries.

    Original languageEnglish
    Article number106011
    JournalData in Brief
    Early online date11 Jul 2020
    Publication statusPublished - Oct 2020

    Bibliographical note

    This is an open access article under the CC BY-NC-ND license.


    National Natural Science Foundation of China [Grant No. 61701435 ], the National R&D Program for Major Research Instruments [Grant No. 61527811], the Zhejiang Provincial Nature Science Foundation of China [Grant No. LY18C110001], and Research Grants Council of the Hong Kong Special Administrative Region, China [Project No. CUHK 14204117]


    • Computational Fluid Dynamics (CFD)
    • Coronary Artery Disease (CAD)
    • Instantaneous Wave-free Ratio (iFR)
    • coronary microcirculation dysfunction (CMD)
    • Coronary artery disease (CAD)
    • Instantaneous wave-free ratio (iFR)
    • Computational fluid dynamics (CFD)
    • Coronary microvascular dysfunction (CMD)

    ASJC Scopus subject areas

    • General


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