Cross validation of ROC generated thresholds for field assessed aerobic fitness related to weight status and cardiovascular disease risk in portuguese young people

Michael J. Duncan, S. Vale, M.P. Santos, J.C. Ribeiro, J. Mota

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    Abstract

    Objectives: To examine the efficacy of aerobic fitness thresholds in predicting weight status and cardiovascular disease risk (CVD) in young people. Methods: A cross-sectional school-based study was conducted on 414 Portuguese young people (235 girls and 179 boys) aged 10-16 years (Mean age±SD=13.6±1. 8 years). Height and mass were assessed to determine body mass index (BMI). The 20m multistage shuttle-fitness test (MSFT) was used as an estimate of aerobic fitness. Capillary blood sampling was used to determine: total cholesterol, triglycerides, high-, and low-density lipoprotein. These were combined with measures of systolic blood pressure as z-scores and summed to create a CVD risk score. Results: Analysis of covariance, controlling for sexual maturation, indicated a significant main effect for BMI as a result of fitness category (P=0.0001). When applied to CVD risk data, there was no difference between "fit" and "unfit" grioups (P=0.136). Subsequent receiver operating curve (ROC) analysis indicated signifciant diagnostic accuracy of 20mMSFT performance for boys and girls (both P=0.0001) with subsequent cut-offs of estimated VO2 peak of 49.5 ml kg-1 min-1 for girls and 47.7 ml kg-1 min-1 for boys. When applied to BMI and CVD risk data, there was a significant main effect as a result of fitness category for BMI (P=0.0001) and CVD risk score (P=0.0001). Conclusions: Recently established cut-points proposed by Boddy et al. (Boddy et al. [2012]: PLoS One 7(9): e45755) show validity in distinguishing between weight status but not CVD risk in Portuguese young people. Alternative ROC generated cut points significantly predicted BMI and CVD risk in this sample.
    Original languageEnglish
    Pages (from-to)751-755
    JournalAmerican Journal of Human Biology
    Volume25
    Issue number6
    DOIs
    Publication statusPublished - 2013

    Bibliographical note

    The full text of this item is not available from the repository.
    ‘This is the peer reviewed version of the following article: Duncan, M.J. , Vale, S. , Santos, M.P. , Ribeiro, J.C. and Mota, J. (2013) Cross validation of ROC generated thresholds for field assessed aerobic fitness related to weight status and cardiovascular disease risk in portuguese young people. American Journal of Human Biology, volume 25 (6): 751-755, which has been published in final form at http://dx.doi.org/10.1002/ajhb.22443. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving'.

    Keywords

    • aerobic fitness
    • weight status
    • cardiovascular disease risk
    • young people

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