COVID-19 and the long-term cardio-respiratory and metabolic health complications

Ruth Ashton, Paul Ansdell, Emily Hume, Thomas Maden-Wilkinson, Declan John Ryan, Esmeq Tuttiett, Mark Faghy

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)


Severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) transmission continues to impact people globally. Whilst the acute symptoms and management strategies are well documented, millions of people globally are experiencing a prolonged and debilitating symptom profile that is reported to last months and even years. COVID-19 is a multi-system disease however the magnitude of the effects and its associated legacy is presently not well understood. Early reports indicate that multidisciplinary approaches between clinical and non-clinical entities are needed to provide effective and rehabilitative patient support pathways and restore pre-COVID-19 quality of life and functional status. Accordingly, this review provides a summary of the impact on cardiovascular, inflammatory, respiratory, and musculoskeletal function following an acute COVID-19 infection along with the prolonged effects of long-COVID.

Original languageEnglish
Article number53
Number of pages8
JournalReviews in Cardiovascular Medicine
Issue number2
Publication statusPublished - 9 Feb 2022
Externally publishedYes

Bibliographical note

Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.


  • COVID-19
  • Cardiometabolic
  • Cardiorespiratory
  • Long-COVID
  • Recovery
  • Rehabilitation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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