CO2 laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion

L. Hao, J. Lawrence

Research output: Contribution to conferencePaper

Abstract

Osteoblast cells were used in an in vitro test to examine changes in cell adhesion on a magnesia partially stabilised zirconia (MgO-PSZ) bioceramic after CO2 laser treatment. The surface roughness, microstructure, crystal size and surface energy of untreated and CO2 laser treated samples were fully characterized. After 24 h cell incubation, no cells were observed on the untreated MgO-PSZ, whereas cells were seen to have attached onto the CO 2 laser treated MgO-PSZ and exhibited spreading and good attachment. Moreover, the cell coverage density implied an increase in cell proliferation with increasing CO2 laser power density. Enhancement of the surface energy of the MgO-PSZ, especially its polar component, caused by the CO 2 laser treatment was found to play a significant role in the initial cell attachment process, thereby leading to enhanced cell growth. Also, the change in topography induced by the CO2 laser treatment was identified as one of the factors influencing the osteoblast cell response.

Original languageEnglish
Publication statusPublished - 1 Dec 2006
Externally publishedYes
Event25th International Congress on Applications of Laser and Electro-Optics - Scottsdale, United States
Duration: 30 Oct 20062 Nov 2006

Conference

Conference25th International Congress on Applications of Laser and Electro-Optics
Abbreviated titleICALEO 2006
CountryUnited States
CityScottsdale
Period30/10/062/11/06

ASJC Scopus subject areas

  • Geochemistry and Petrology
  • Electrical and Electronic Engineering

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    Hao, L., & Lawrence, J. (2006). CO2 laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion. Paper presented at 25th International Congress on Applications of Laser and Electro-Optics, Scottsdale, United States.