Comparative efflux of saquinavir, ritonavir and lopinavir from primary human cells

B. Diker, Omar Janneh, R.P.G. van Heeswijk, K.F.T. Copeland

    Research output: Contribution to journalArticle

    4 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)241-245
    JournalDrug Metabolism Letters
    Issue number4
    Publication statusPublished - 2010

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    • Protease inhibitor
    • HIV-1
    • release
    • peripheral blood
    • saquinavir
    • ritonavir
    • lopinavir
    • Therapeutic drug monitoring
    • plasma drug concentrations
    • Peripheral blood mononuclear cells
    • cell-associated drug concentrations
    • Highly active antiretroviral therapy (HAART)
    • non-nucleoside
    • lymphocytes
    • Multi-drug resistance
    • breast cancer resistance protein (BCRP)
    • lipophilicity
    • anti-coagulated
    • Octanol-Saline Partition Coefficient
    • efflux proteins
    • drug-containing bathing media

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