Cocoa and Chocolate their clinical benefits: Insights in study design

Duane Mellor, Ekavi Georgousopoulou, Nenad Naumovski

Research output: Contribution to journalReview article

205 Downloads (Pure)

Abstract

Randomised controlled trials and meta-analyses have demonstrated the potential
protective effect of cocoa and chocolate consumption with respect to Cardiovascular Disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which includes reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate has the been assessed for its potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.

Publisher statement: This material has been published in CAB Reviews, Vol 12, Issue 018, 1-7, the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl. www.cabi.org/CABReviews
Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalCAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources
Volume12
Issue number018
DOIs
Publication statusPublished - 3 Jul 2017

Fingerprint

cocoa
cardiovascular disease
chocolate
experimental design
cardiovascular diseases
Cardiovascular Diseases
Peer Review
experimental study
peers
stroke
Meta-Analysis
mechanism of action
risk factors
Randomized Controlled Trials
Stroke
Health
dosage
consumption
effect
Chocolate

Bibliographical note

Accepted for publication in CAB Reviews as of 26th April 2017. After publication, authors may update this notice to read, This material has been published in CAB Reviews, 12 (18), July 2017 the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl - www.cabi.org/CABReviews.

Cite this

Cocoa and Chocolate their clinical benefits : Insights in study design. / Mellor, Duane; Georgousopoulou, Ekavi; Naumovski, Nenad.

In: CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, Vol. 12, No. 018, 03.07.2017, p. 1-7.

Research output: Contribution to journalReview article

@article{02b775b06cc34849bd182408d069c655,
title = "Cocoa and Chocolate their clinical benefits: Insights in study design",
abstract = "Randomised controlled trials and meta-analyses have demonstrated the potentialprotective effect of cocoa and chocolate consumption with respect to Cardiovascular Disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which includes reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate has the been assessed for its potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.Publisher statement: This material has been published in CAB Reviews, Vol 12, Issue 018, 1-7, the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl. www.cabi.org/CABReviews",
author = "Duane Mellor and Ekavi Georgousopoulou and Nenad Naumovski",
note = "Accepted for publication in CAB Reviews as of 26th April 2017. After publication, authors may update this notice to read, This material has been published in CAB Reviews, 12 (18), July 2017 the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl - www.cabi.org/CABReviews.",
year = "2017",
month = "7",
day = "3",
doi = "10.1079/PAVSNNR201712018",
language = "English",
volume = "12",
pages = "1--7",
journal = "CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources",
issn = "1749-8848",
publisher = "CAB International",
number = "018",

}

TY - JOUR

T1 - Cocoa and Chocolate their clinical benefits

T2 - Insights in study design

AU - Mellor, Duane

AU - Georgousopoulou, Ekavi

AU - Naumovski, Nenad

N1 - Accepted for publication in CAB Reviews as of 26th April 2017. After publication, authors may update this notice to read, This material has been published in CAB Reviews, 12 (18), July 2017 the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl - www.cabi.org/CABReviews.

PY - 2017/7/3

Y1 - 2017/7/3

N2 - Randomised controlled trials and meta-analyses have demonstrated the potentialprotective effect of cocoa and chocolate consumption with respect to Cardiovascular Disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which includes reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate has the been assessed for its potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.Publisher statement: This material has been published in CAB Reviews, Vol 12, Issue 018, 1-7, the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl. www.cabi.org/CABReviews

AB - Randomised controlled trials and meta-analyses have demonstrated the potentialprotective effect of cocoa and chocolate consumption with respect to Cardiovascular Disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which includes reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate has the been assessed for its potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.Publisher statement: This material has been published in CAB Reviews, Vol 12, Issue 018, 1-7, the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl. www.cabi.org/CABReviews

U2 - 10.1079/PAVSNNR201712018

DO - 10.1079/PAVSNNR201712018

M3 - Review article

VL - 12

SP - 1

EP - 7

JO - CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources

JF - CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources

SN - 1749-8848

IS - 018

ER -