Clinico-radiological Observations in Meconium Aspiration Syndrome

Susana Lama; Shyam Kumar Mahato; Nagendra Chaudhary; Nikhil Agrawal; Santosh Pathak; Om Prakash Kurmi; Baldev Bhatia; Kailash Nath Agarwal

doi:10.31729/jnma.3340

Clinico-radiological Observations in Meconium Aspiration Syndrome

Susana Lama, Shyam Kumar Mahato, Nagendra Chaudhary, Nikhil Agrawal, Santosh Pathak, Om Prakash Kurmi, Baldev Bhatia, Kailash Nath Agarwal

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Abstract

INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal.

METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied.

RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.

Original language	English
Pages (from-to)	510-515
Number of pages	6
Journal	JNMA; journal of the Nepal Medical Association
Volume	56
Issue number	209
DOIs	https://doi.org/10.31729/jnma.3340
Publication status	Published - 28 Feb 2018
Externally published	Yes

Bibliographical note

This work is licensed under a Creative Commons Attribution 4.0 International License.

JNMA allow to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose. The author(s) are allowed to retain publishing rights without restrictions. The JNMA work is licensed under a Creative Commons Attribution 4.0 International License. More about Copyright Policy.

Keywords

Apgar Score
Asphyxia Neonatorum/epidemiology
Birth Weight
Female
Gestational Age
Humans
Infant, Newborn
Male
Meconium
Meconium Aspiration Syndrome/diagnosis
Nepal/epidemiology
Radiography, Thoracic/methods
Risk Factors

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title = "Clinico-radiological Observations in Meconium Aspiration Syndrome",

abstract = "INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal.METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied.RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.",

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author = "Susana Lama and Mahato, {Shyam Kumar} and Nagendra Chaudhary and Nikhil Agrawal and Santosh Pathak and Kurmi, {Om Prakash} and Baldev Bhatia and Agarwal, {Kailash Nath}",

note = "This work is licensed under a Creative Commons Attribution 4.0 International License. JNMA allow to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose. The author(s) are allowed to retain publishing rights without restrictions. The JNMA work is licensed under a Creative Commons Attribution 4.0 International License. More about Copyright Policy.",

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day = "28",

doi = "10.31729/jnma.3340",

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T1 - Clinico-radiological Observations in Meconium Aspiration Syndrome

AU - Lama, Susana

AU - Mahato, Shyam Kumar

AU - Chaudhary, Nagendra

AU - Agrawal, Nikhil

AU - Pathak, Santosh

AU - Kurmi, Om Prakash

AU - Bhatia, Baldev

AU - Agarwal, Kailash Nath

N1 - This work is licensed under a Creative Commons Attribution 4.0 International License. JNMA allow to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose. The author(s) are allowed to retain publishing rights without restrictions. The JNMA work is licensed under a Creative Commons Attribution 4.0 International License. More about Copyright Policy.

PY - 2018/2/28

Y1 - 2018/2/28

N2 - INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal.METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied.RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.

AB - INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal.METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied.RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) Conclusions: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.

KW - Apgar Score

KW - Asphyxia Neonatorum/epidemiology

KW - Birth Weight

KW - Female

KW - Gestational Age

KW - Humans

KW - Infant, Newborn

KW - Male

KW - Meconium

KW - Meconium Aspiration Syndrome/diagnosis

KW - Nepal/epidemiology

KW - Radiography, Thoracic/methods

KW - Risk Factors

U2 - 10.31729/jnma.3340

DO - 10.31729/jnma.3340

M3 - Article

C2 - 30058634

SN - 0028-2715

VL - 56

SP - 510

EP - 515

JO - JNMA; journal of the Nepal Medical Association

JF - JNMA; journal of the Nepal Medical Association

IS - 209

ER -

Clinico-radiological Observations in Meconium Aspiration Syndrome

Abstract

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