Characterisation of brain D2 dopamine receptors solubilised by lysophosphatidylcholine

Mark Wheatley, Philip G. Strange

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Brain D2 dopamine receptors have been solubilised using lysophosphatidylcholine. The inclusion of proteinase inhibitors during solubilisation enables a preparation to be obtained containing a high proportion of solubilised D2 receptors with pharmacological properties similar to those of membrane bound D2 receptors.

Original languageEnglish
Pages (from-to)97-101
Number of pages5
JournalFEBS Letters
Issue number1
Publication statusPublished - 10 Jan 1983
Externally publishedYes

Bibliographical note

Free access


  • D dopamine receptor
  • Lysophosphatidylcholine [H]Spiperone Bovine caudate nucleus
  • Solubilisation

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology


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