Brain D2 dopamine receptors have been solubilised using lysophosphatidylcholine. The inclusion of proteinase inhibitors during solubilisation enables a preparation to be obtained containing a high proportion of solubilised D2 receptors with pharmacological properties similar to those of membrane bound D2 receptors.
Bibliographical noteFree access
- D dopamine receptor
- Lysophosphatidylcholine [H]Spiperone Bovine caudate nucleus
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology
- Cell Biology