Changes of Arterial Pulse Waveform Characteristics with Gestational Age during Normal Pregnancy

Kunyan Li, Song Zhang, Lin Yang, Hongqing Jiang, Zhenyu Chi, Anran Wang, Yimin Yang, Xuwen Li , Dongmei Hao, Lei Zhang, Dingchang Zheng

Research output: Contribution to journalArticle

3 Citations (Scopus)
2 Downloads (Pure)

Abstract

Arterial pulse waveform analysis has been widely used to reflect physiological changes in the cardiovascular system. This study aimed to comprehensively investigate the changes of waveform characteristics of both photoplethysmographic (PPG) and radial pulses with gestational age during normal pregnancy. PPG and radial pulses were simultaneously recorded from 130 healthy pregnant women at seven gestational time points. After normalizing the arterial pulse waveforms, the abscissa of notch point, the total pulse area and the reflection index were extracted and compared between different measurement points and between the PPG and radial pulses using post-hoc multiple comparisons with Bonferrioni correction. The results showed that the effect of gestational age on all the three waveform characteristics was significant (all p < 0.001) after adjusting for maternal age, heart rate and blood pressures. All the three waveform characteristics demonstrated similar changing trends with gestational age, and they were all significantly different between the measurements from gestational week 12–15 and the others (all p < 0.05, except for the PPG total pulse area between the first and second measurement points). In conclusion, this study has comprehensively quantified similar changes of both PPG and radial pulse waveform characteristics with gestational age.
Original languageEnglish
Article number 15571
Number of pages7
JournalScientific Reports
Volume8
DOIs
Publication statusPublished - 22 Oct 2018
Externally publishedYes

Bibliographical note

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Fingerprint Dive into the research topics of 'Changes of Arterial Pulse Waveform Characteristics with Gestational Age during Normal Pregnancy'. Together they form a unique fingerprint.

  • Cite this