Blood Flow Restriction Attenuates Muscle Damage in Resistance Exercise Performed Until Concentric Muscle Failure.

Victor M Curty, Paulo Vinicios Camuzi Zovico, Rafael Barrera Salgueiro, Leonardo Carvalho Caldas, Richard Diego Leite, Nuno F de Sousa, Lucas Guimarães-Ferreira, Valério Garrone Barauna

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    International Journal of Exercise Science 16(2): 469-481, 2023. The present study aimed to evaluate whether blood flow restriction (BFR) can prevent exercise-induced muscle damage in resistance exercise (RE) performed until concentric muscle failure (CMF). Twenty healthy volunteers (25 ± 4 years, 80.4 ± 11.8 kg, 175 ± 8 cm) performed three sets of unilateral biceps curl exercise (40% of 1RM) with (RE + BFR) and without (RE) BFR until CMF. A third condition was to perform the same number of repetitions as RE + BFR without using BFR (matched). Performing fewer repetitions, RE + BFR caused muscle fatigue post-exercise as high as that caused by RE. In addition, the range of motion, upper arm circumference, pressure pain threshold, and maximal voluntary contraction were immediately affected by our exercise protocol with BFR, returning rapidly to basal values within 24 h, while in RE, muscle damage markers remained elevated until 48 h post-exercise. The same results were observed concerning serum creatine kinase and lactate dehydrogenase activity. Thus, BFR + RE performed until CMF attenuated muscle damage following similar metabolic stress to RE alone performed until CMF, with less work volume.
    Original languageEnglish
    Pages (from-to)469-481
    Number of pages13
    JournalInternational Journal of Exercise Science
    Issue number2
    Publication statusPublished - Mar 2023

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    • eccentric contraction
    • muscle fatigue
    • injury
    • kaatsu
    • strength training


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