Biomimetics for the induction of bone formation

U Ripamonti, L Roden

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The new strategy to initiate the induction of bone formation is to carve smart, self-inducing geometric cues assembled within biomimetic medical devices. These are endowed with the striking prerogative of differentiating myoblastic and/or pericytic stem cells into osteoblastic-like cells attached to the morphogenetic concavities; osteoblastic-like cells secrete osteogenic gene products of the TGF-β supergene family, further differentiating invading stem cells into osteoblastic-like cells, and initiating bone formation by induction as a secondary response.
Original languageEnglish
Pages (from-to)469-479
Number of pages11
JournalExpert Review of Medical Devices
Volume7
Issue number4
DOIs
Publication statusPublished - 2010
Externally publishedYes

Fingerprint Dive into the research topics of 'Biomimetics for the induction of bone formation'. Together they form a unique fingerprint.

  • Cite this