Biocompatibility enhancement of an inert ceramic using CO 2 laser radiation

L. Hao, J. Lawrence

Research output: Contribution to journalConference articlepeer-review


Due to their attractive mechanical properties, bioinert ceramics are frequently used in the high load-bearing sites such as orthopaedic and dental implants, but they are chemically inert and do not naturally form a direct bond with bone and thus are lack of osseointegration. A CO 2 laser was used to modify the surface properties of bioinert zirconia with the aim to achieve osseointegration between the material and bone. Higher wettability characteristics generated by the CO 2 laser treatment was primarily due to the enhancement of the surface energy, particularly the polar component, determined by way of microstructural changes. An in vitro test using human fetal osteoblast cells (hFOB) revealed that osteoblast cells adhere better on the laser treated sample than the untreated sample. The change in the wettability characteristics could be the main mechanism governing the osteoblast cell adhesion on the YPSZ.

Original languageEnglish
Article number52
Pages (from-to)381-391
Number of pages11
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 13 Jan 2005
Externally publishedYes
EventLasers in Material Processing and Manufacturing II - Beijing, China
Duration: 10 Nov 200412 Nov 2004


  • Laser
  • Osteoblast cell adhesion
  • Wettability characteristics
  • Yttria partially stabilised zirconia (YPSZ)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


Dive into the research topics of 'Biocompatibility enhancement of an inert ceramic using CO 2 laser radiation'. Together they form a unique fingerprint.

Cite this