Bases moleculares das ações da testosterona, hormônio do crescimento e IGF-1 sobre a hipertrofia muscular esquelética e respostas ao treinamento de força

The hormones testosterone, growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are important regulators of muscle mass, modulating processes of protein synthesis and degradation. This paper aims to discuss the molecular basis of actions of these hormones in skeletal muscle, the responses of acute and chronic, as well as possible influences upon neuromuscular adaptations to strength training. The manipulation of the training variables such as volume, intensity, rest intervals and muscle groups used directly affects the hormonal responses. Increased secretion of anabolic hormones could contribute to chronic adaptations -- muscle hypertrophy -- in response to training. However, the importance of hormonal response to this adaptation is still uncertain and needs further investigation. ABSTRACT FROM AUTHOR