Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study

Mina Movahedian; Jessica Thomas; Jamal Rahmani; Cain C T Clark; Bahram Rashidkhani; Matin Ghanavati

doi:10.1016/j.dsx.2020.02.013

Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study

Mina Movahedian, Jessica Thomas, Jamal Rahmani, Cain C T Clark, Bahram Rashidkhani, Matin Ghanavati

Research output: Contribution to journal › Article › peer-review

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Abstract

AIM: To identify the association between the dietary carbohydrate indexes, such as dietary glycemic index (DGI) and load (DGL), dietary insulin index (DII) and load (DIL), with the possibility of cataract.

METHOD: This case-control study consisted of 101 new cases of cataract and 202 controls. DGI and DGL were computed through DGI values previously published. DII was also calculated based on dietary insulin index data published previously.

RESULTS: There was a significant positive association between the highest quartiles of DGI (OR = 6.56; 95% CI = 2.67-16.06; P < 0.001), DGL (OR = 6.17; 95% CI = 1.93-19.37; P = 0.002) and DIL (OR = 4.17; 95% CI = 1.41-12.27; P = 0.004) with risk of cataract, compared to those on the lowest quartile, but not for DII (OR = 0.85; 95% CI = 0.39-1.86; P = 0.82). Furthermore, after stratifying groups by BMI, a significant direct association between highest quartile of DGI (OR = 6.76; 95% CI = 2.49-18.38; P < 0.001) and DGL (OR = 3.45; 95% CI = 0.96-12.37; P = 0.05) with risk of cataract was evident in individuals with elevated BMI (BMI≥25).

CONCLUSION: We found a significant, direct, relationship between DGI, DGL and DIL with risk of cataract. However, the association between DII and the risk of cataract was not significant, even after adjusting for related confounders.

Original language	English
Pages (from-to)	199-204
Number of pages	6
Journal	Diabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume	14
Issue number	3
Early online date	26 Feb 2020
DOIs	https://doi.org/10.1016/j.dsx.2020.02.013
Publication status	Published - May 2020

Bibliographical note

NOTICE: this is the author’s version of a work that was accepted for publication in Diabetes and Metabolic Syndrome: Clinical Research and Reviews. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14:3 (2020) DOI: 10.1016/j.dsx.2020.02.013

© 2020, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Keywords

Cataract
DII
DIL
GI
GL

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dsx.2020.02.013

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Movahedian, M., Thomas, J., Rahmani, J., Clark, C. C. T., Rashidkhani, B., & Ghanavati, M. (2020). Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14(3), 199-204. https://doi.org/10.1016/j.dsx.2020.02.013

Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract : Results from a case-control study. / Movahedian, Mina; Thomas, Jessica; Rahmani, Jamal et al.

In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews, Vol. 14, No. 3, 05.2020, p. 199-204.

Research output: Contribution to journal › Article › peer-review

Movahedian, M, Thomas, J, Rahmani, J, Clark, CCT, Rashidkhani, B & Ghanavati, M 2020, 'Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study', Diabetes and Metabolic Syndrome: Clinical Research and Reviews, vol. 14, no. 3, pp. 199-204. https://doi.org/10.1016/j.dsx.2020.02.013

Movahedian M, Thomas J, Rahmani J, Clark CCT, Rashidkhani B, Ghanavati M. Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2020 May;14(3):199-204. Epub 2020 Feb 26. doi: 10.1016/j.dsx.2020.02.013

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abstract = "AIM: To identify the association between the dietary carbohydrate indexes, such as dietary glycemic index (DGI) and load (DGL), dietary insulin index (DII) and load (DIL), with the possibility of cataract.METHOD: This case-control study consisted of 101 new cases of cataract and 202 controls. DGI and DGL were computed through DGI values previously published. DII was also calculated based on dietary insulin index data published previously.RESULTS: There was a significant positive association between the highest quartiles of DGI (OR = 6.56; 95% CI = 2.67-16.06; P < 0.001), DGL (OR = 6.17; 95% CI = 1.93-19.37; P = 0.002) and DIL (OR = 4.17; 95% CI = 1.41-12.27; P = 0.004) with risk of cataract, compared to those on the lowest quartile, but not for DII (OR = 0.85; 95% CI = 0.39-1.86; P = 0.82). Furthermore, after stratifying groups by BMI, a significant direct association between highest quartile of DGI (OR = 6.76; 95% CI = 2.49-18.38; P < 0.001) and DGL (OR = 3.45; 95% CI = 0.96-12.37; P = 0.05) with risk of cataract was evident in individuals with elevated BMI (BMI≥25).CONCLUSION: We found a significant, direct, relationship between DGI, DGL and DIL with risk of cataract. However, the association between DII and the risk of cataract was not significant, even after adjusting for related confounders.",

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AU - Thomas, Jessica

AU - Rahmani, Jamal

AU - Clark, Cain C T

AU - Rashidkhani, Bahram

AU - Ghanavati, Matin

N1 - NOTICE: this is the author’s version of a work that was accepted for publication in Diabetes and Metabolic Syndrome: Clinical Research and Reviews. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14:3 (2020) DOI: 10.1016/j.dsx.2020.02.013 © 2020, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

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N2 - AIM: To identify the association between the dietary carbohydrate indexes, such as dietary glycemic index (DGI) and load (DGL), dietary insulin index (DII) and load (DIL), with the possibility of cataract.METHOD: This case-control study consisted of 101 new cases of cataract and 202 controls. DGI and DGL were computed through DGI values previously published. DII was also calculated based on dietary insulin index data published previously.RESULTS: There was a significant positive association between the highest quartiles of DGI (OR = 6.56; 95% CI = 2.67-16.06; P < 0.001), DGL (OR = 6.17; 95% CI = 1.93-19.37; P = 0.002) and DIL (OR = 4.17; 95% CI = 1.41-12.27; P = 0.004) with risk of cataract, compared to those on the lowest quartile, but not for DII (OR = 0.85; 95% CI = 0.39-1.86; P = 0.82). Furthermore, after stratifying groups by BMI, a significant direct association between highest quartile of DGI (OR = 6.76; 95% CI = 2.49-18.38; P < 0.001) and DGL (OR = 3.45; 95% CI = 0.96-12.37; P = 0.05) with risk of cataract was evident in individuals with elevated BMI (BMI≥25).CONCLUSION: We found a significant, direct, relationship between DGI, DGL and DIL with risk of cataract. However, the association between DII and the risk of cataract was not significant, even after adjusting for related confounders.

AB - AIM: To identify the association between the dietary carbohydrate indexes, such as dietary glycemic index (DGI) and load (DGL), dietary insulin index (DII) and load (DIL), with the possibility of cataract.METHOD: This case-control study consisted of 101 new cases of cataract and 202 controls. DGI and DGL were computed through DGI values previously published. DII was also calculated based on dietary insulin index data published previously.RESULTS: There was a significant positive association between the highest quartiles of DGI (OR = 6.56; 95% CI = 2.67-16.06; P < 0.001), DGL (OR = 6.17; 95% CI = 1.93-19.37; P = 0.002) and DIL (OR = 4.17; 95% CI = 1.41-12.27; P = 0.004) with risk of cataract, compared to those on the lowest quartile, but not for DII (OR = 0.85; 95% CI = 0.39-1.86; P = 0.82). Furthermore, after stratifying groups by BMI, a significant direct association between highest quartile of DGI (OR = 6.76; 95% CI = 2.49-18.38; P < 0.001) and DGL (OR = 3.45; 95% CI = 0.96-12.37; P = 0.05) with risk of cataract was evident in individuals with elevated BMI (BMI≥25).CONCLUSION: We found a significant, direct, relationship between DGI, DGL and DIL with risk of cataract. However, the association between DII and the risk of cataract was not significant, even after adjusting for related confounders.

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Association between dietary glycemic index and glycemic load, insulin index and load with incidence of age-related cataract: Results from a case-control study

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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