An LBM based model for initial stenosis development in the carotid artery

Katerina Stamou; James Buick

doi:10.1088/1751-8113/49/19/195602

An LBM based model for initial stenosis development in the carotid artery

Katerina Stamou, James Buick

University of Portsmouth

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

20 Downloads (Pure)

Abstract

A numerical scheme is proposed to simulate the early stages of stenosis development based on the properties of blood flow in the carotid artery, computed using the lattice Boltzmann method. The model is developed on the premise, supported by evidence from the literature, that the stenosis develops in regions of low velocity and low wall shear stress. The model is based on two spatial parameters which relate to the extent to which the stenosis can grow in each development phase. Simulations of stenosis development are presented for a range of the spacial parameters to determine suitable ranges for their application. Flow fields are also presented which indicate that the stenosis is developing in a realistic manner, providing evidence that stenosis development is indeed influenced by the low shear stress, rather than occurring in such
areas coincidentally.

Original language	English
Article number	195602
Journal	Journal of Physics A: Mathematical and Theoretical
Volume	49
Issue number	19
DOIs	https://doi.org/10.1088/1751-8113/49/19/195602
Publication status	Published - 6 Apr 2016
Externally published	Yes

Bibliographical note

This is the Accepted Manuscript version of an article accepted for publication in Journal of Physics A: Mathematical and Theoretical. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at 10.1088/1751-8113/49/19/195602.

Copyright © and Moral Rights are retained by the author(s) and/ or other copyright owners. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This item cannot be reproduced or quoted extensively from without first obtaining permission in writing from the copyright holder(s). The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the copyright holders.

Keywords

Stenosis modelling
Blood flow modelling
Atherosclerosis,
lattice Boltzmann method

Access to Document

10.1088/1751-8113/49/19/195602

Post-PrintAccepted author manuscript, 2.51 MBLicence: Unspecified

Cite this

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title = "An LBM based model for initial stenosis development in the carotid artery",

abstract = "A numerical scheme is proposed to simulate the early stages of stenosis development based on the properties of blood flow in the carotid artery, computed using the lattice Boltzmann method. The model is developed on the premise, supported by evidence from the literature, that the stenosis develops in regions of low velocity and low wall shear stress. The model is based on two spatial parameters which relate to the extent to which the stenosis can grow in each development phase. Simulations of stenosis development are presented for a range of the spacial parameters to determine suitable ranges for their application. Flow fields are also presented which indicate that the stenosis is developing in a realistic manner, providing evidence that stenosis development is indeed influenced by the low shear stress, rather than occurring in suchareas coincidentally.",

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author = "Katerina Stamou and James Buick",

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Y1 - 2016/4/6

N2 - A numerical scheme is proposed to simulate the early stages of stenosis development based on the properties of blood flow in the carotid artery, computed using the lattice Boltzmann method. The model is developed on the premise, supported by evidence from the literature, that the stenosis develops in regions of low velocity and low wall shear stress. The model is based on two spatial parameters which relate to the extent to which the stenosis can grow in each development phase. Simulations of stenosis development are presented for a range of the spacial parameters to determine suitable ranges for their application. Flow fields are also presented which indicate that the stenosis is developing in a realistic manner, providing evidence that stenosis development is indeed influenced by the low shear stress, rather than occurring in suchareas coincidentally.

AB - A numerical scheme is proposed to simulate the early stages of stenosis development based on the properties of blood flow in the carotid artery, computed using the lattice Boltzmann method. The model is developed on the premise, supported by evidence from the literature, that the stenosis develops in regions of low velocity and low wall shear stress. The model is based on two spatial parameters which relate to the extent to which the stenosis can grow in each development phase. Simulations of stenosis development are presented for a range of the spacial parameters to determine suitable ranges for their application. Flow fields are also presented which indicate that the stenosis is developing in a realistic manner, providing evidence that stenosis development is indeed influenced by the low shear stress, rather than occurring in suchareas coincidentally.

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KW - Blood flow modelling

KW - Atherosclerosis,

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ER -

An LBM based model for initial stenosis development in the carotid artery

Abstract

Bibliographical note

Keywords

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