An improved non-comparative classification method for human microRNA gene prediction

Rukshan Batuwita, Vasile Palade

Research output: Chapter in Book/Report/Conference proceedingConference proceeding

6 Citations (Scopus)

Abstract

micoRNA (miRNA) is a vital class of non-coding RNA gènes, which participâtes in post-transcriptional gene regulation in eukaryotic cell. Interestingly, some close relationships between miRNA expression levels and several human diseases like cancers have been recently uncovered. Diffkulties of identifying miRNAs via direct experimental method due to their special and temporal expression patterns make the computational prediction methods paramount important. Specially, non-comparative computational methods would have the advantage of recognizing species-specific miRNAs that can be missed by comparative methods. In this paper we present a systematic development of an improved classifier System for non-comparative human miRNA gene recognition using effective machine learning techniques.

Original languageEnglish
Title of host publication8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
ISBN (Electronic)978-1-4244-2845-8
DOIs
Publication statusPublished - 2008
Externally publishedYes
Event8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 - Athens, Greece
Duration: 8 Oct 200810 Oct 2008

Conference

Conference8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
CountryGreece
CityAthens
Period8/10/0810/10/08

    Fingerprint

Keywords

  • humans
  • RNA
  • Cancer
  • character generation
  • diseases
  • proteins
  • genomics
  • bioinformatics
  • prediction methods
  • laboratories
  • molecular biophysics
  • cancer
  • genetics
  • learning (artificial intelligence)
  • machine learning
  • noncomparative classification method
  • human microRNA gene prediction
  • post-transcriptional gene regulation
  • eukaryotic cell
  • cancers
  • human miRNA gene recognition

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Batuwita, R., & Palade, V. (2008). An improved non-comparative classification method for human microRNA gene prediction. In 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 [4696724] https://doi.org/10.1109/BIBE.2008.4696724