A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images

Maria Panayiotou, Andrew P King, R James Housden, YingLiang Ma, Michael Cooklin, Mark O'Neill, Jaswinder Gill, C Aldo Rinaldi, Kawal S Rhode

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

PURPOSE: Image-guided cardiac interventions involve the use of fluoroscopic images to guide the insertion and movement of interventional devices. Cardiorespiratory gating can be useful for 3D reconstruction from multiple x-ray views and for reducing misalignments between 3D anatomical models overlaid onto fluoroscopy.

METHODS: The authors propose a novel and potentially clinically useful retrospective cardiorespiratory gating technique. The principal component analysis (PCA) statistical method is used in combination with other image processing operations to make our proposed masked-PCA technique suitable for cardiorespiratory gating. Unlike many previously proposed techniques, our technique is robust to varying image-content, thus it does not require specific catheters or any other optically opaque structures to be visible. Therefore, it works without any knowledge of catheter geometry. The authors demonstrate the application of our technique for the purposes of retrospective cardiorespiratory gating of normal and very low dose x-ray fluoroscopy images.

RESULTS: For normal dose x-ray images, the algorithm was validated using 28 clinical electrophysiology x-ray fluoroscopy sequences (2168 frames), from patients who underwent radiofrequency ablation (RFA) procedures for the treatment of atrial fibrillation and cardiac resynchronization therapy procedures for heart failure. The authors established end-systole, end-expiration, and end-inspiration success rates of 97.0%, 97.9%, and 97.0%, respectively. For very low dose applications, the technique was tested on ten x-ray sequences from the RFA procedures with added noise at signal to noise ratio (SNR) values of √50, √10, √8, √6, √5, √2 and √1 to simulate the image quality of increasingly lower dose x-ray images. Even at the low SNR value of √2, representing a dose reduction of more than 25 times, gating success rates of 89.1%, 88.8%, and 86.8% were established.

CONCLUSIONS: The proposed technique can therefore extract useful information from interventional x-ray images while minimizing exposure to ionizing radiation.

Original languageEnglish
Pages (from-to)071901- 071913
Number of pages13
JournalMedical Physics
Volume41
Issue number7
Early online date6 Jun 2014
DOIs
Publication statusPublished - Jul 2014

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X-Rays
Fluoroscopy
Signal-To-Noise Ratio
Principal Component Analysis
Catheters
Anatomic Models
Cardiac Resynchronization Therapy
Systole
Electrophysiology
Ionizing Radiation
Atrial Fibrillation
Noise
Heart Failure
Equipment and Supplies
Therapeutics

Bibliographical note

This is the peer reviewed version of the following article: Panayiotou, M, King, AP, Housden, RJ, Ma, Y, Cooklin, M, O'Neill, M, Gill, J, Rinaldi, CA & Rhode, KS 2016, 'A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images' Medical Physics, vol 41, no. 7, pp. 071901- 071913 which has been published in final form at https://dx.doi.org/10.1118/1.4881140
This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

Keywords

  • Algorithms
  • Atrial Fibrillation
  • Cardiac Resynchronization Therapy
  • Catheter Ablation
  • Computer Simulation
  • Fluoroscopy
  • Heart
  • Heart Failure
  • Humans
  • Image Processing, Computer-Assisted
  • Motion
  • Poisson Distribution
  • Principal Component Analysis
  • Radiation Dosage
  • Respiration
  • Signal-To-Noise Ratio
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Validation Studies

Cite this

Panayiotou, M., King, A. P., Housden, R. J., Ma, Y., Cooklin, M., O'Neill, M., ... Rhode, K. S. (2014). A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images. Medical Physics, 41(7), 071901- 071913. https://doi.org/10.1118/1.4881140

A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images. / Panayiotou, Maria; King, Andrew P; Housden, R James; Ma, YingLiang; Cooklin, Michael; O'Neill, Mark; Gill, Jaswinder; Rinaldi, C Aldo; Rhode, Kawal S.

In: Medical Physics, Vol. 41, No. 7, 07.2014, p. 071901- 071913.

Research output: Contribution to journalArticle

Panayiotou, M, King, AP, Housden, RJ, Ma, Y, Cooklin, M, O'Neill, M, Gill, J, Rinaldi, CA & Rhode, KS 2014, 'A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images' Medical Physics, vol. 41, no. 7, pp. 071901- 071913. https://doi.org/10.1118/1.4881140
Panayiotou, Maria ; King, Andrew P ; Housden, R James ; Ma, YingLiang ; Cooklin, Michael ; O'Neill, Mark ; Gill, Jaswinder ; Rinaldi, C Aldo ; Rhode, Kawal S. / A statistical method for retrospective cardiac and respiratory motion gating of interventional cardiac x-ray images. In: Medical Physics. 2014 ; Vol. 41, No. 7. pp. 071901- 071913.
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N2 - PURPOSE: Image-guided cardiac interventions involve the use of fluoroscopic images to guide the insertion and movement of interventional devices. Cardiorespiratory gating can be useful for 3D reconstruction from multiple x-ray views and for reducing misalignments between 3D anatomical models overlaid onto fluoroscopy.METHODS: The authors propose a novel and potentially clinically useful retrospective cardiorespiratory gating technique. The principal component analysis (PCA) statistical method is used in combination with other image processing operations to make our proposed masked-PCA technique suitable for cardiorespiratory gating. Unlike many previously proposed techniques, our technique is robust to varying image-content, thus it does not require specific catheters or any other optically opaque structures to be visible. Therefore, it works without any knowledge of catheter geometry. The authors demonstrate the application of our technique for the purposes of retrospective cardiorespiratory gating of normal and very low dose x-ray fluoroscopy images.RESULTS: For normal dose x-ray images, the algorithm was validated using 28 clinical electrophysiology x-ray fluoroscopy sequences (2168 frames), from patients who underwent radiofrequency ablation (RFA) procedures for the treatment of atrial fibrillation and cardiac resynchronization therapy procedures for heart failure. The authors established end-systole, end-expiration, and end-inspiration success rates of 97.0%, 97.9%, and 97.0%, respectively. For very low dose applications, the technique was tested on ten x-ray sequences from the RFA procedures with added noise at signal to noise ratio (SNR) values of √50, √10, √8, √6, √5, √2 and √1 to simulate the image quality of increasingly lower dose x-ray images. Even at the low SNR value of √2, representing a dose reduction of more than 25 times, gating success rates of 89.1%, 88.8%, and 86.8% were established.CONCLUSIONS: The proposed technique can therefore extract useful information from interventional x-ray images while minimizing exposure to ionizing radiation.

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