The use of ultrasound-assisted extraction (UAE) for the extraction of Chlorogenic Acid (CA) from Cynara scolymus L., (artichoke) leaves using 80% methanol at room temperature over 15 minutes gave a significant increase in yield (up to a 50%) compared with maceration at room temperature and close to that obtained by boiling over the same time period. A note of caution is introduced when comparing UAE with Soxhlet extraction because, in the latter case, the liquid entering the Soxhlet extractor is more concentrated in methanol (nearly 100%) that the solvent in the reservoir (80% methanol) due to fractionation during distillation. The mechanism of UAE is discussed in terms of the effects of cavitation on the swelling index, solvent diffusion and the removal of a stagnant layer of solvent surrounding the plant material.
Bibliographical noteNOTICE: this is the author’s version of a work that was accepted for publication in Ultrasonics Sonochemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Ultrasonics Sonochemistry, [31, (2016)] DOI: 10.1016/j.ultsonch.2016.01.002
© 2016, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
- Chlorogenic acid
- Ultrasound-assisted extraction
- General extraction mechanism
- Cynara scolymus L.
Saleh, I. A., Vinatoru, M., Mason, T. J., Aboutabl, E. A., & Hammouda, F. M. (2016). A possible general mechanism for ultrasound-assisted extraction (UAE) suggested from the results of UAE of chlorogenic acid from Cynara scolymus L. (artichoke) leaves. Ultrasonics Sonochemistry, 31, 330-336. https://doi.org/10.1016/j.ultsonch.2016.01.002