A PCR-based field evaluation of Theileria infections in cattle and ticks in Kenya

D. Watt, H. Kiara, O. A.E. Sparagano

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Theileria parva is a hemoprotozoan parasite responsible for causing East Coast fever in east and central Africa. The vaccine currently available is an 'infection and treatment' procedure which involves the injection of live sporozoites followed by drug therapy to prevent clinical illness. Before introducing potentially new strains of parasite into an area, however, it is crucial to check the disease situation in the field first. We looked at three different areas in Kenya: Limuru in which many cattle have already been vaccinated and Kitale and Kakamega which so far have not been vaccinated. Genus and species specific primers were used to test for the presence of Theileria species in blood and tick samples collected from the three areas. Limuru showed a cattle and tick infection prevalence of 27% and 2.3% respectively with T. parva. Kitale showed a cattle and tick infection prevalence of 100% and 14.2% respectively while Kakamega showed 100% and 0% respectively. Reasons for variations between areas involving vaccination status and epidemiological data are discussed.

Original languageEnglish
Pages (from-to)69-77
Number of pages9
JournalAnnals of the New York Academy of Sciences
Volume849
DOIs
Publication statusPublished - 1 Jan 1998
Externally publishedYes

Fingerprint

Theileria
Kenya
Ticks
Theileria parva
Drug therapy
Polymerase Chain Reaction
Parasites
Infection
Theileriasis
Central Africa
Coastal zones
Sporozoites
Eastern Africa
Blood
Vaccines
Vaccination
Drug Therapy
Injections
Evaluation
Cattle

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

A PCR-based field evaluation of Theileria infections in cattle and ticks in Kenya. / Watt, D.; Kiara, H.; Sparagano, O. A.E.

In: Annals of the New York Academy of Sciences, Vol. 849, 01.01.1998, p. 69-77.

Research output: Contribution to journalArticle

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