A long road to recovery? Reduced quality of life, impaired functional status and the lived experience of Long COVID patients, a cohort analysis

Mark Faghy; R. Owen; James Yates; Callum Thomas; Francesco Vincenzo Ferraro; Ruth Ashton

doi:10.1183/13993003.congress-2022.4429

Abstract

Introduction: One in ten people will develop symptoms of Long COVID (LC) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite widely reported symptomology, the impact upon quality of life (QoL) and functional status (FS) is not well documented. Accordingly, we conducted a cohort observation to determine the impact of LC on QoL and FS that also captured the lived experience. Method: Fifty-six patients (n=41 female, mean age 51±10 years) with confirmed history of COVID-19 were recruited from LC clinics in the United Kingdom and completed a 16-week cohort observation (five face-to-face visits and bi-weekly telephone consultations). QoL was assessed via the EQ-5D-5L and FS via the post-COVID functional status scale (PCFS) and the six-minute walk test (6MWT). Symptom profile and lived experience was captured via self-report diaries and analysed via thematic analysis. Results: QoL across all domains was 2.5±0.6 AU at baseline and unchanged at 16-weeks (2.4±0.9, P=0.12). PCFS was improved at 16-weeks (2.1 ±1.1 AU) when compared to baseline (2.7±0.4 AU, P=0.02) but highlighted impaired FS. 6MWT was 322±133 M at baseline and improved at 16 weeks (430±150 meters, P

Original language	English
DOIs	https://doi.org/10.1183/13993003.congress-2022.4429
Publication status	Published - 1 Dec 2022
Externally published	Yes
Event	2022 ERS International Congress - Bacelona, Spain Duration: 4 Sept 2022 → 6 Sept 2022 https://europeanlung.org/en/get-involved/events/ers-congress-2022/

Conference

Conference	2022 ERS International Congress
Country/Territory	Spain
City	Bacelona
Period	4/09/22 → 6/09/22
Internet address	https://europeanlung.org/en/get-involved/events/ers-congress-2022/

Bibliographical note

This article was presented at the 2022 ERS International Congress, in session “-”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

Copyright ©the authors 2022

Access to Document

10.1183/13993003.congress-2022.4429

Cite this

@conference{8853a0b625b547878872b4941dea5bdb,

title = "A long road to recovery? Reduced quality of life, impaired functional status and the lived experience of Long COVID patients, a cohort analysis",

abstract = "Introduction: One in ten people will develop symptoms of Long COVID (LC) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite widely reported symptomology, the impact upon quality of life (QoL) and functional status (FS) is not well documented. Accordingly, we conducted a cohort observation to determine the impact of LC on QoL and FS that also captured the lived experience. Method: Fifty-six patients (n=41 female, mean age 51±10 years) with confirmed history of COVID-19 were recruited from LC clinics in the United Kingdom and completed a 16-week cohort observation (five face-to-face visits and bi-weekly telephone consultations). QoL was assessed via the EQ-5D-5L and FS via the post-COVID functional status scale (PCFS) and the six-minute walk test (6MWT). Symptom profile and lived experience was captured via self-report diaries and analysed via thematic analysis. Results: QoL across all domains was 2.5±0.6 AU at baseline and unchanged at 16-weeks (2.4±0.9, P=0.12). PCFS was improved at 16-weeks (2.1 ±1.1 AU) when compared to baseline (2.7±0.4 AU, P=0.02) but highlighted impaired FS. 6MWT was 322±133 M at baseline and improved at 16 weeks (430±150 meters, P",

author = "Mark Faghy and R. Owen and James Yates and Callum Thomas and Ferraro, {Francesco Vincenzo} and Ruth Ashton",

note = "This article was presented at the 2022 ERS International Congress, in session “-”. This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). Copyright {\textcopyright}the authors 2022; 2022 ERS International Congress ; Conference date: 04-09-2022 Through 06-09-2022",

year = "2022",

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doi = "10.1183/13993003.congress-2022.4429",

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T1 - A long road to recovery? Reduced quality of life, impaired functional status and the lived experience of Long COVID patients, a cohort analysis

AU - Faghy, Mark

AU - Owen, R.

AU - Yates, James

AU - Thomas, Callum

AU - Ferraro, Francesco Vincenzo

AU - Ashton, Ruth

N1 - This article was presented at the 2022 ERS International Congress, in session “-”. This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). Copyright ©the authors 2022

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Introduction: One in ten people will develop symptoms of Long COVID (LC) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite widely reported symptomology, the impact upon quality of life (QoL) and functional status (FS) is not well documented. Accordingly, we conducted a cohort observation to determine the impact of LC on QoL and FS that also captured the lived experience. Method: Fifty-six patients (n=41 female, mean age 51±10 years) with confirmed history of COVID-19 were recruited from LC clinics in the United Kingdom and completed a 16-week cohort observation (five face-to-face visits and bi-weekly telephone consultations). QoL was assessed via the EQ-5D-5L and FS via the post-COVID functional status scale (PCFS) and the six-minute walk test (6MWT). Symptom profile and lived experience was captured via self-report diaries and analysed via thematic analysis. Results: QoL across all domains was 2.5±0.6 AU at baseline and unchanged at 16-weeks (2.4±0.9, P=0.12). PCFS was improved at 16-weeks (2.1 ±1.1 AU) when compared to baseline (2.7±0.4 AU, P=0.02) but highlighted impaired FS. 6MWT was 322±133 M at baseline and improved at 16 weeks (430±150 meters, P

AB - Introduction: One in ten people will develop symptoms of Long COVID (LC) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite widely reported symptomology, the impact upon quality of life (QoL) and functional status (FS) is not well documented. Accordingly, we conducted a cohort observation to determine the impact of LC on QoL and FS that also captured the lived experience. Method: Fifty-six patients (n=41 female, mean age 51±10 years) with confirmed history of COVID-19 were recruited from LC clinics in the United Kingdom and completed a 16-week cohort observation (five face-to-face visits and bi-weekly telephone consultations). QoL was assessed via the EQ-5D-5L and FS via the post-COVID functional status scale (PCFS) and the six-minute walk test (6MWT). Symptom profile and lived experience was captured via self-report diaries and analysed via thematic analysis. Results: QoL across all domains was 2.5±0.6 AU at baseline and unchanged at 16-weeks (2.4±0.9, P=0.12). PCFS was improved at 16-weeks (2.1 ±1.1 AU) when compared to baseline (2.7±0.4 AU, P=0.02) but highlighted impaired FS. 6MWT was 322±133 M at baseline and improved at 16 weeks (430±150 meters, P

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DO - 10.1183/13993003.congress-2022.4429

M3 - Abstract

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