A case of transplacental transmission of Theileria equi in a foal in Trinidad

Karla C. Georges, Chuckwudozi D. Ezeokoli, Olivier Sparagano, Indira Pargass, Mervyn Campbell, Roger D'Abadie, Michael J. Yabsley

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-Giemsa ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalVeterinary Parasitology
Volume175
Issue number3-4
DOIs
Publication statusPublished - 10 Feb 2011
Externally publishedYes

Fingerprint

Theileria
Theileria equi
Trinidad and Tobago
transplacental transmission
Babesiosis
equine piroplasmosis
foals
Horses
Babesia
jaundice
Jaundice
mares
Babesia caballi
Parasitemia
Piroplasmida
Diagnostic Errors
rRNA Genes
parasitemia
blood
DNA

Keywords

  • Equine piroplasmosis
  • Neonatal foals
  • Reverse line blot
  • Trinidad

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)

Cite this

Georges, K. C., Ezeokoli, C. D., Sparagano, O., Pargass, I., Campbell, M., D'Abadie, R., & Yabsley, M. J. (2011). A case of transplacental transmission of Theileria equi in a foal in Trinidad. Veterinary Parasitology, 175(3-4), 363-366. https://doi.org/10.1016/j.vetpar.2010.10.019

A case of transplacental transmission of Theileria equi in a foal in Trinidad. / Georges, Karla C.; Ezeokoli, Chuckwudozi D.; Sparagano, Olivier; Pargass, Indira; Campbell, Mervyn; D'Abadie, Roger; Yabsley, Michael J.

In: Veterinary Parasitology, Vol. 175, No. 3-4, 10.02.2011, p. 363-366.

Research output: Contribution to journalArticle

Georges, KC, Ezeokoli, CD, Sparagano, O, Pargass, I, Campbell, M, D'Abadie, R & Yabsley, MJ 2011, 'A case of transplacental transmission of Theileria equi in a foal in Trinidad' Veterinary Parasitology, vol. 175, no. 3-4, pp. 363-366. https://doi.org/10.1016/j.vetpar.2010.10.019
Georges KC, Ezeokoli CD, Sparagano O, Pargass I, Campbell M, D'Abadie R et al. A case of transplacental transmission of Theileria equi in a foal in Trinidad. Veterinary Parasitology. 2011 Feb 10;175(3-4):363-366. https://doi.org/10.1016/j.vetpar.2010.10.019
Georges, Karla C. ; Ezeokoli, Chuckwudozi D. ; Sparagano, Olivier ; Pargass, Indira ; Campbell, Mervyn ; D'Abadie, Roger ; Yabsley, Michael J. / A case of transplacental transmission of Theileria equi in a foal in Trinidad. In: Veterinary Parasitology. 2011 ; Vol. 175, No. 3-4. pp. 363-366.
@article{f17110cd479546f9ba89646c9d2651a1,
title = "A case of transplacental transmission of Theileria equi in a foal in Trinidad",
abstract = "Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10h post-partum. A high parasitaemia (63{\%}) of piroplasms was observed in a Wright-Giemsa {\circledR} stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.",
keywords = "Equine piroplasmosis, Neonatal foals, Reverse line blot, Trinidad",
author = "Georges, {Karla C.} and Ezeokoli, {Chuckwudozi D.} and Olivier Sparagano and Indira Pargass and Mervyn Campbell and Roger D'Abadie and Yabsley, {Michael J.}",
year = "2011",
month = "2",
day = "10",
doi = "10.1016/j.vetpar.2010.10.019",
language = "English",
volume = "175",
pages = "363--366",
journal = "Veterinary Parasitology: Regional Studies and Reports",
issn = "0304-4017",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - A case of transplacental transmission of Theileria equi in a foal in Trinidad

AU - Georges, Karla C.

AU - Ezeokoli, Chuckwudozi D.

AU - Sparagano, Olivier

AU - Pargass, Indira

AU - Campbell, Mervyn

AU - D'Abadie, Roger

AU - Yabsley, Michael J.

PY - 2011/2/10

Y1 - 2011/2/10

N2 - Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-Giemsa ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

AB - Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-Giemsa ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

KW - Equine piroplasmosis

KW - Neonatal foals

KW - Reverse line blot

KW - Trinidad

UR - http://www.scopus.com/inward/record.url?scp=78751638081&partnerID=8YFLogxK

U2 - 10.1016/j.vetpar.2010.10.019

DO - 10.1016/j.vetpar.2010.10.019

M3 - Article

VL - 175

SP - 363

EP - 366

JO - Veterinary Parasitology: Regional Studies and Reports

JF - Veterinary Parasitology: Regional Studies and Reports

SN - 0304-4017

IS - 3-4

ER -