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  • Richard Aspinall
2016

An age-associated decline in thymic output differs in dog breeds according to their longevity

Holder, A., Mella, S., Palmer, D. B., Aspinall, R. & Catchpole, B., 8 Nov 2016, In : PLoS ONE. 11, 11, e0165968.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
7 Downloads (Pure)
2011

Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden

Ngom, P. T., Solon, J., Moore, S. E., Morgan, G., Prentice, A. M. & Aspinall, R., 15 Jun 2011, In : Journal of Biomedical Science. 18, 1, 41.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
4 Downloads (Pure)
2018

Perturbation of the T cell receptor repertoire occurs with increasing age in dogs

Holder, A., Mirczuk, S. M., Fowkes, R. C., Palmer, D. B., Aspinall, R. & Catchpole, B., 1 Feb 2018, In : Developmental and Comparative Immunology. 79, p. 150-157 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
22 Downloads (Pure)
2017

Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It?

Lang, P. O., Loulergue, P. & Aspinall, R., 1 Nov 2017, In : Journal of the American Geriatrics Society. 65, 11, p. 2529-2534 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Protection versus pathology in aviremic and high viral load HIV-2 infection - The pivotal role of immune activation and T-cell kinetics

Hegedus, A., Nyamweya, S., Zhang, Y., Govind, S., Aspinall, R., Mashanova, A., Jansen, V. A. A., Whittle, H., Jaye, A., Flanagan, K. L. & Macallan, D. C., 1 Sep 2014, In : Journal of Infectious Diseases. 210, 5, p. 752-761 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
10 Downloads (Pure)
2017

A qualitative analysis of the effectiveness of telehealthcare devices (II) barriers to uptake of telehealthcare devices

Campling, N. C., Pitts, D. G., Knight, P. V. & Aspinall, R., 6 Jul 2017, In : BMC Health Services Research. 17, 1, 466.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
7 Downloads (Pure)
2018

Vaccination choices for older people, looking beyond age specific approaches

Aspinall, R. & Lang, P. O., 2 Jan 2018, In : Expert Review of Vaccines. 17, 1, p. 23-30 8 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders

Prusty, B., Gulve, N., Govind, S., Krueger, G., Feichtinger, J., Larcombe, L., Aspinall, R., Ablashi, D. & Toro, C., 21 Aug 2018, In : Frontiers in Microbiology. 9, 1955.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
13 Downloads (Pure)
2014

Cellular signalling pathways in immune aging and regeneration

Aspinall, R., Lapenna, A., B-Lynch, C. & Lang, P. O., 2014, In : Biochemical Society. Transactions. 42, 3, p. 651-656 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Vaccination in the elderly: What can be recommended?

Lang, P. O. & Aspinall, R., 2014, In : Drugs and Aging. 31, 8, p. 581-599 19 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2013

Reversing T cell immunosenescence: Why, who, and how

Lang, P. O., Govind, S. & Aspinall, R., Jun 2013, In : Age. 35, 3, p. 609-620 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2012

Immunotherapy of immunosenesence; who, how and when?

Govind, S., Lapenna, A., Lang, P. O. & Aspinall, R., 2012, In : Open Longevity Science. 6, p. 56-63 8 p.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
9 Downloads (Pure)
2015

Can we translate vitamin D immunomodulating effect on innate and adaptive immunity to vaccine response?

Lang, P. O. & Aspinall, R., 20 Mar 2015, In : Nutrients. 7, 3, p. 2044-2060 17 p.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
4 Downloads (Pure)
2011

Real time-PCR assay estimating the naive T-cell pool in whole blood and dried blood spot samples: Pilot study in young adults

Lang, P. O., Mitchell, W. A., Govind, S. & Aspinall, R., 30 Jun 2011, In : Journal of Immunological Methods. 369, 1-2, p. 133-140 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2012

Efficacité des vaccins antigrippes chez la personne âgée

Lang, P. O., Govind, S. & Aspinall, R., Jun 2012, In : NPG Neurologie - Psychiatrie - Geriatrie. 12, 69, p. 121-130 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2013

Saurons-nous jamais ce qui provoque le vieillissement?

Lang, P. O., Proust, J., Vogel, T. & Aspinall, R., Dec 2013, In : NPG Neurologie - Psychiatrie - Geriatrie. 13, 78, p. 337-343 7 p.

Research output: Contribution to journalShort survey

2 Citations (Scopus)
2018

Interventions to restore appropriate immune function in the elderly

Aspinall, R. & Lang, P. O., 25 Jan 2018, In : Immunity and Ageing. 15, 1, 5.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
19 Downloads (Pure)
2013

Dose response kinetics of CD8 lymphocytes from young animals transfused into old animals and challenged with influenza

Aspinall, R., Govind, S., Lapenna, A. & Lang, P. O., 16 Aug 2013, In : Immunity and Ageing. 10, 1, 34.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
4 Downloads (Pure)
2012

Comparison of manual and automated DNA purification for measuring TREC in dried blood spot (DBS) samples with qPCR

Lang, P. O., Govind, S., Dramé, M. & Aspinall, R., 31 Oct 2012, In : Journal of Immunological Methods. 384, 1-2, p. 118-127 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effectiveness of influenza vaccine in aging and older adults: Comprehensive analysis of the evidence

Lang, P. O., Mendes, A., Socquet, J., Assir, N., Govind, S. & Aspinall, R., 2012, In : Clinical Interventions in Aging. 7, p. 55-64 10 p.

Research output: Contribution to journalReview article

Open Access
File
60 Citations (Scopus)
18 Downloads (Pure)

Immunosenescence and herd immunity: With an ever-increasing aging population do we need to rethink vaccine schedules?

Lang, P. O. & Aspinall, R., Feb 2012, In : Expert Review of Vaccines. 11, 2, p. 167-176 10 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)
2011

Immunosenescence: Implications for vaccination programmes in adults

Lang, P. O., Govind, S., Michel, J. P., Aspinall, R. & Mitchell, W. A., Apr 2011, In : Maturitas. 68, 4, p. 322-330 9 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)
2013

Immune Senescence and Vaccination in the Elderly

Lang, P. O., Govind, S., Bokum, A. T., Kenny, N., Matas, E., Pitts, D. & Aspinall, R., 1 Oct 2013, In : Current Topics in Medicinal Chemistry. 13, 20, p. 2541-2550 10 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)

A respiratory monitoring device based on clavicular motion

Pitts, D. G., Patel, M. K., Lang, P. O., Sinclair, A. J. & Aspinall, R., Aug 2013, In : Physiological Measurement. 34, 8, N51.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

Vaccine responsiveness in the elderly: Best practice for the clinic

Aspinall, R. & Lang, P. O., 2014, In : Expert Review of Vaccines. 13, 7, p. 885-894 10 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)
2018
1 Citation (Scopus)
2011

Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring

Aspinall, R., Prentice, A. M. & Ngom, P. T., 30 Jun 2011, In : PLoS ONE. 6, 6, 0020812.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
2 Downloads (Pure)
2013

Measuring the TREC ratio in dried blood spot samples: Intra- and inter-filter paper cards reproducibility

Lang, P. O., Govind, S., Dramé, M. & Aspinall, R., 29 Mar 2013, In : Journal of Immunological Methods. 389, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 othersSimm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., 1 Nov 2015, In : Mechanisms of Ageing and Development. 151, p. 2-12 11 p.

Research output: Contribution to journalArticle

Open Access
File
100 Citations (Scopus)
7 Downloads (Pure)
2012

L'immunosénescence

Lang, P. O., Govind, S. & Aspinall, R., Aug 2012, In : NPG Neurologie - Psychiatrie - Geriatrie. 12, 70, p. 171-181 11 p.

Research output: Contribution to journalShort survey

9 Citations (Scopus)
2018

Polymorphisms in the canine IL7R 3′UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185

Holder, A., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R. & Catchpole, B., 1 Apr 2018, In : Developmental and Comparative Immunology. 81, p. 244-251 8 p.

Research output: Contribution to journalArticle

Open Access
2017

Vitamin D Status and the Host Resistance to Infections: What It Is Currently (Not) Understood

Lang, P. O. & Aspinall, R., 1 May 2017, In : Clinical Therapeutics. 39, 5, p. 930-945 16 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2012

Immunosenescence and the 3Rs: Restoration, replacement and reprogramming immunosenescence and its correction

Mitchell, W. A., Pink, R. C., Lapenna, A. & Aspinall, R., 1 Jan 2012, Immunosenescence. Thiel, A. (ed.). Springer Basel, p. 175-200 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

A qualitative analysis of the effectiveness of telehealthcare devices (i) are they meeting the needs of end-users?

Campling, N. C., Pitts, D. G., Knight, P. V. & Aspinall, R., 4 Jul 2017, In : BMC Health Services Research. 17, 1, 455.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
16 Downloads (Pure)
2013

A Simple Model System Enabling Human CD34+ Cells to Undertake Differentiation Towards T Cells

Lapenna, A., B-Lynch, C., Kapeni, C. & Aspinall, R., 23 Jul 2013, In : PLoS ONE. 8, 7, e69572.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
9 Downloads (Pure)

The avalanche is coming... and just now it's starting to snow

Aspinall, R. & Lang, P. O., 2013, In : Frontiers in Immunology. 4, JUN, 65.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
7 Downloads (Pure)
2016

Zinc supplementation induces regulatory T cells by inhibition of Sirt-1 deacetylase in mixed lymphocyte cultures

Rosenkranz, E., Metz, C. H. D., Maywald, M., Hilgers, R. D., Weßels, I., Senff, T., Haase, H., Jager, M., Ott, M., Aspinall, R., Plumakers, B. & Rink, L., 1 Mar 2016, In : Molecular Nutrition and Food Research. 60, 3, p. 661-671 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2011

Vaccine effectiveness in older individuals: What has been learned from the influenza-vaccine experience

Lang, P. O., Govind, S., Mitchell, W. A., Siegrist, C. A. & Aspinall, R., Jul 2011, In : Ageing Research Reviews. 10, 3, p. 389-395 7 p.

Research output: Contribution to journalReview article

47 Citations (Scopus)
2013

How important is vitamin D in preventing infections?

Lang, P. O., Samaras, N., Samaras, D. & Aspinall, R., May 2013, In : Osteoporosis International. 24, 5, p. 1537-1553 17 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)