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  • Richard Aspinall
2012

Immunotherapy of immunosenesence; who, how and when?

Govind, S., Lapenna, A., Lang, P. O. & Aspinall, R., 2012, In : Open Longevity Science. 6, p. 56-63 8 p.

Research output: Contribution to journalReview article

Open Access
File
10 Citations (Scopus)
7 Downloads (Pure)

L'immunosénescence

Lang, P. O., Govind, S. & Aspinall, R., Aug 2012, In : NPG Neurologie - Psychiatrie - Geriatrie. 12, 70, p. 171-181 11 p.

Research output: Contribution to journalShort survey

9 Citations (Scopus)
2013

The avalanche is coming... and just now it's starting to snow

Aspinall, R. & Lang, P. O., 2013, In : Frontiers in Immunology. 4, JUN, 65.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
7 Downloads (Pure)
2018

Polymorphisms in the canine IL7R 3′UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185

Holder, A., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R. & Catchpole, B., 1 Apr 2018, In : Developmental and Comparative Immunology. 81, p. 244-251 8 p.

Research output: Contribution to journalArticle

Open Access

Vaccination choices for older people, looking beyond age specific approaches

Aspinall, R. & Lang, P. O., 2 Jan 2018, In : Expert Review of Vaccines. 17, 1, p. 23-30 8 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)
2017

A qualitative analysis of the effectiveness of telehealthcare devices (i) are they meeting the needs of end-users?

Campling, N. C., Pitts, D. G., Knight, P. V. & Aspinall, R., 4 Jul 2017, In : BMC Health Services Research. 17, 1, 455.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
16 Downloads (Pure)
2013

A respiratory monitoring device based on clavicular motion

Pitts, D. G., Patel, M. K., Lang, P. O., Sinclair, A. J. & Aspinall, R., Aug 2013, In : Physiological Measurement. 34, 8, N51.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

Efficacité des vaccins antigrippes chez la personne âgée

Lang, P. O., Govind, S. & Aspinall, R., Jun 2012, In : NPG Neurologie - Psychiatrie - Geriatrie. 12, 69, p. 121-130 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2013

Reversing T cell immunosenescence: Why, who, and how

Lang, P. O., Govind, S. & Aspinall, R., Jun 2013, In : Age. 35, 3, p. 609-620 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Saurons-nous jamais ce qui provoque le vieillissement?

Lang, P. O., Proust, J., Vogel, T. & Aspinall, R., Dec 2013, In : NPG Neurologie - Psychiatrie - Geriatrie. 13, 78, p. 337-343 7 p.

Research output: Contribution to journalShort survey

2 Citations (Scopus)
2018

Perturbation of the T cell receptor repertoire occurs with increasing age in dogs

Holder, A., Mirczuk, S. M., Fowkes, R. C., Palmer, D. B., Aspinall, R. & Catchpole, B., 1 Feb 2018, In : Developmental and Comparative Immunology. 79, p. 150-157 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
21 Downloads (Pure)
2011

Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring

Aspinall, R., Prentice, A. M. & Ngom, P. T., 30 Jun 2011, In : PLoS ONE. 6, 6, 0020812.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
2 Downloads (Pure)
2015

Can we translate vitamin D immunomodulating effect on innate and adaptive immunity to vaccine response?

Lang, P. O. & Aspinall, R., 20 Mar 2015, In : Nutrients. 7, 3, p. 2044-2060 17 p.

Research output: Contribution to journalReview article

Open Access
File
17 Citations (Scopus)
4 Downloads (Pure)
2018
1 Citation (Scopus)
2015

MARK-AGE biomarkers of ageing

Bürkle, A., Moreno-Villanueva, M., Bernhard, J., Blasco, M., Zondag, G., Hoeijmakers, J. H. J., Toussaint, O., Grubeck-Loebenstein, B., Mocchegiani, E., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Dollé, M., Salmon, M., Kristensen, P., Griffiths, H. R., Libert, C., Grune, T., Breusing, N. & 10 othersSimm, A., Franceschi, C., Capri, M., Talbot, D., Caiafa, P., Friguet, B., Slagboom, P. E., Hervonen, A., Hurme, M. & Aspinall, R., 1 Nov 2015, In : Mechanisms of Ageing and Development. 151, p. 2-12 11 p.

Research output: Contribution to journalArticle

Open Access
File
98 Citations (Scopus)
7 Downloads (Pure)
2016

Zinc supplementation induces regulatory T cells by inhibition of Sirt-1 deacetylase in mixed lymphocyte cultures

Rosenkranz, E., Metz, C. H. D., Maywald, M., Hilgers, R. D., Weßels, I., Senff, T., Haase, H., Jager, M., Ott, M., Aspinall, R., Plumakers, B. & Rink, L., 1 Mar 2016, In : Molecular Nutrition and Food Research. 60, 3, p. 661-671 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2017

Vitamin D Status and the Host Resistance to Infections: What It Is Currently (Not) Understood

Lang, P. O. & Aspinall, R., 1 May 2017, In : Clinical Therapeutics. 39, 5, p. 930-945 16 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2014

Cellular signalling pathways in immune aging and regeneration

Aspinall, R., Lapenna, A., B-Lynch, C. & Lang, P. O., 2014, In : Biochemical Society. Transactions. 42, 3, p. 651-656 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Dose response kinetics of CD8 lymphocytes from young animals transfused into old animals and challenged with influenza

Aspinall, R., Govind, S., Lapenna, A. & Lang, P. O., 16 Aug 2013, In : Immunity and Ageing. 10, 1, 34.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
4 Downloads (Pure)
2012

Immunosenescence and the 3Rs: Restoration, replacement and reprogramming immunosenescence and its correction

Mitchell, W. A., Pink, R. C., Lapenna, A. & Aspinall, R., 1 Jan 2012, Immunosenescence. Thiel, A. (ed.). Springer Basel, p. 175-200 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Vaccine effectiveness in older individuals: What has been learned from the influenza-vaccine experience

Lang, P. O., Govind, S., Mitchell, W. A., Siegrist, C. A. & Aspinall, R., Jul 2011, In : Ageing Research Reviews. 10, 3, p. 389-395 7 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Immunosenescence: Implications for vaccination programmes in adults

Lang, P. O., Govind, S., Michel, J. P., Aspinall, R. & Mitchell, W. A., Apr 2011, In : Maturitas. 68, 4, p. 322-330 9 p.

Research output: Contribution to journalReview article

44 Citations (Scopus)
2013

How important is vitamin D in preventing infections?

Lang, P. O., Samaras, N., Samaras, D. & Aspinall, R., May 2013, In : Osteoporosis International. 24, 5, p. 1537-1553 17 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2011

Real time-PCR assay estimating the naive T-cell pool in whole blood and dried blood spot samples: Pilot study in young adults

Lang, P. O., Mitchell, W. A., Govind, S. & Aspinall, R., 30 Jun 2011, In : Journal of Immunological Methods. 369, 1-2, p. 133-140 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2013

Measuring the TREC ratio in dried blood spot samples: Intra- and inter-filter paper cards reproducibility

Lang, P. O., Govind, S., Dramé, M. & Aspinall, R., 29 Mar 2013, In : Journal of Immunological Methods. 389, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

A qualitative analysis of the effectiveness of telehealthcare devices (II) barriers to uptake of telehealthcare devices

Campling, N. C., Pitts, D. G., Knight, P. V. & Aspinall, R., 6 Jul 2017, In : BMC Health Services Research. 17, 1, 466.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
7 Downloads (Pure)

Chikungunya Virus Infection: Why Should U.S. Geriatricians Be Aware of It?

Lang, P. O., Loulergue, P. & Aspinall, R., 1 Nov 2017, In : Journal of the American Geriatrics Society. 65, 11, p. 2529-2534 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018

Interventions to restore appropriate immune function in the elderly

Aspinall, R. & Lang, P. O., 25 Jan 2018, In : Immunity and Ageing. 15, 1, 5.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
18 Downloads (Pure)
2012

Immunosenescence and herd immunity: With an ever-increasing aging population do we need to rethink vaccine schedules?

Lang, P. O. & Aspinall, R., Feb 2012, In : Expert Review of Vaccines. 11, 2, p. 167-176 10 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)

Effectiveness of influenza vaccine in aging and older adults: Comprehensive analysis of the evidence

Lang, P. O., Mendes, A., Socquet, J., Assir, N., Govind, S. & Aspinall, R., 2012, In : Clinical Interventions in Aging. 7, p. 55-64 10 p.

Research output: Contribution to journalReview article

Open Access
File
57 Citations (Scopus)
18 Downloads (Pure)

Comparison of manual and automated DNA purification for measuring TREC in dried blood spot (DBS) samples with qPCR

Lang, P. O., Govind, S., Dramé, M. & Aspinall, R., 31 Oct 2012, In : Journal of Immunological Methods. 384, 1-2, p. 118-127 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

A Simple Model System Enabling Human CD34+ Cells to Undertake Differentiation Towards T Cells

Lapenna, A., B-Lynch, C., Kapeni, C. & Aspinall, R., 23 Jul 2013, In : PLoS ONE. 8, 7, e69572.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
9 Downloads (Pure)
2014

Vaccination in the elderly: What can be recommended?

Lang, P. O. & Aspinall, R., 2014, In : Drugs and Aging. 31, 8, p. 581-599 19 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Protection versus pathology in aviremic and high viral load HIV-2 infection - The pivotal role of immune activation and T-cell kinetics

Hegedus, A., Nyamweya, S., Zhang, Y., Govind, S., Aspinall, R., Mashanova, A., Jansen, V. A. A., Whittle, H., Jaye, A., Flanagan, K. L. & Macallan, D. C., 1 Sep 2014, In : Journal of Infectious Diseases. 210, 5, p. 752-761 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
10 Downloads (Pure)
2016

An age-associated decline in thymic output differs in dog breeds according to their longevity

Holder, A., Mella, S., Palmer, D. B., Aspinall, R. & Catchpole, B., 8 Nov 2016, In : PLoS ONE. 11, 11, e0165968.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
7 Downloads (Pure)
2011

Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden

Ngom, P. T., Solon, J., Moore, S. E., Morgan, G., Prentice, A. M. & Aspinall, R., 15 Jun 2011, In : Journal of Biomedical Science. 18, 1, 41.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
3 Downloads (Pure)
2014

Vaccine responsiveness in the elderly: Best practice for the clinic

Aspinall, R. & Lang, P. O., 2014, In : Expert Review of Vaccines. 13, 7, p. 885-894 10 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)
2018

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders

Prusty, B., Gulve, N., Govind, S., Krueger, G., Feichtinger, J., Larcombe, L., Aspinall, R., Ablashi, D. & Toro, C., 21 Aug 2018, In : Frontiers in Microbiology. 9, 1955.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
11 Downloads (Pure)
2013

Immune Senescence and Vaccination in the Elderly

Lang, P. O., Govind, S., Bokum, A. T., Kenny, N., Matas, E., Pitts, D. & Aspinall, R., 1 Oct 2013, In : Current Topics in Medicinal Chemistry. 13, 20, p. 2541-2550 10 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)