Research output per year
Research output per year
Personal profile
Research Interests
My laboratory studies the complex genetic and molecular mechanisms regulating cellular stress responses to identify potential new disease biomarkers and therapeutic targets. This includes identifying:
- DNA damage response pathways that suppress cancer
- Genes and mutations that influence radiotherapy and chemotherapy responses
- How and why fasting alters cell health & cancer therapy effectiveness
We employ various complimentary model systems (yeast, flies, human cell culture and mice) and modern genetic, genomic, complex trait analysis, molecular biology, cell biology and CRISPR-Cas9 genome editing approaches.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Genetics, Doctorate, The distinct roles of MRX, Tel1 and Sae2 at uncapped telomeres in budding yeast, Newcastle University
… → 2007
Biomedical Science, Degree
1998 → 2002
External positions
Honorary Lecturer, University of Leicester
Sept 2018 → …
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MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?
Abbas, H., Alhamoudi, K., Evans, M., Jones, G. & Foster, S., 16 Apr 2018, In: BMC Cancer. 18, 423Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)125 Downloads (Pure) -
PHENOS: a high-throughput and flexible tool for microorganism growth phenotyping on solid media
Barton, D., Georghiou, D., Dave, N., Alghamdi, M., Walsh, T., Louis, E. & Foster, S., 24 Jan 2018, In: BMC Microbiology. 18, 9Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)102 Downloads (Pure) -
Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression
Foster, S., De, S., Johnson, L. K., Petrini, J. H. J. & Stracker, T. H., 19 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 25, p. 9953-9958Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)57 Downloads (Pure) -
Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage
Foster, S., Balestrini, A. & Petrini, J. H. J., Nov 2011, In: Molecular and Cellular Biology. 31, 21, p. 4379-4389 11 p.Research output: Contribution to journal › Article › peer-review
90 Citations (Scopus) -
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair
Foster, S., Lee, J. H., Choy, M. L., Ngo, L. & Marks, P. A., 17 Aug 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 33, p. 14639-14644 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile308 Citations (Scopus)79 Downloads (Pure)