Sharon Williams


  • 343 Citations
  • 8 h-Index
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Personal profile


I have a PhD in Biochemistry. I worked as a post doctorate research fellow in both the Chemistry and the Biology departments of Warwick University between 2002 and 2010. My research focused on the biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes. I have a wide range and depth of research experience in molecular biology, biochemistry, and chemistry.

I am member of the Royal Society of Chemistry and I am involved in many projects related to the society. I have joined Coventry University as a lecturer in November 2014 to continue my research into exploring enzymes mechanism in general and lignin degradation in particular.

Area of Expertise:

Biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes.

Research Interests

Enzymes mechanisms and protein structure

Vision Statement

I am very interested in applications for industrial biotechnology that could be developed and characterize novel bioproducts obtained by enzymatic oxidation of lignin. In addition, lignin degradation would release valuable low molecular weight aromatic chemicals that would add considerable value to biofuel production.

My other interest is the twin-arginine translocation, or Tat pathway. In this pathway, substrates are synthesised with N-terminal signal peptides containing a key twin-arginine motif. The proteins are then transported by a membrane-bound Tat translocon which is uniquely able to transport fully folded proteins across the tightly coupled plasma membrane. One of the interests is how the system can be exploited for the production of high-value therapeutic proteins and also development of drug targets.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Escherichia coli Medicine & Life Sciences
Bacillus subtilis Medicine & Life Sciences
Valine Medicine & Life Sciences
Dioxygenases Chemical Compounds
Proteins Medicine & Life Sciences
Phosphoglycerate Dehydrogenase Medicine & Life Sciences
Bacilli Chemical Compounds
Enzymes Medicine & Life Sciences

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Research Output 2001 2019

  • 343 Citations
  • 8 h-Index
  • 12 Article
  • 1 Commissioned report
  • 1 Review article

Higher Education Outreach: Examining Key Challenges For Academics

Johnson, M. , Danvers, E. , Hinton-Smith, T. , Atkinson, K. , Bowden, G. , Foster, J. , Garner, K. , Garrud, P. , Greaves, S. , Harris, P. , Hejmadi, M. , Hill, D. , Hughes, G. , Jackson, L. , O'Sullivan, A. , O'Tuama, S. , Brown, P. P. , Philipson, P. , Ravenscroft, S. , Rhys, M. & 6 others Ritchie, T., Talbot, J., Walker, D., Watson, J., Williams, M. & Williams, S. 4 Feb 2019 In : British journal of educational studies. (In-Press), p. (In-Press)

Research output: Contribution to journalArticle

tuition fee
impact research

Protein engineering of Pseudomonas fluorescens peroxidase Dyp1B for oxidation of phenolic and polymeric lignin substrates

Pour, R. R., Ehibhatiomhan, A., Huang, Y., Ashley, B., Rashid, G., Mendel Williams, S. & Bugg, T. D. H. 9 Jan 2019 In : Enzyme and Microbial Technology. 123, p. 21-29 9 p.

Research output: Contribution to journalArticle

protein engineering
Pseudomonas fluorescens

Association for Academic Outreach Evidence Submission to the UPP Foundation Civic University Commission 2018 Association for Academic Outreach

Williams, S., Talbot, J., Awesti, A., Bowden, G., Danvers, E., Foster, J. M., Hejmadi, M., Hinton-Smith, T., Lazarus, J., Melhuish, C., Moffat, C. R., O'Tuama, S., Walker, D., Watson, J. & Harris, N. 31 Jul 2018

Research output: Book/ReportCommissioned report

8 Citations

Expression of the bifunctional Bacillus subtilis TatAd protein in Escherichia coli reveals distinct TatA/B-family and TatB-specific domains

Barnett, J. P., Lawrence, J., Mendel, S. & Robinson, C. Aug 2011 In : Archives of Microbiology. 193, 8, p. 583-594 12 p.

Research output: Contribution to journalArticle

Escherichia coli Proteins
Bacillus subtilis
Escherichia coli
Gram-Negative Bacteria
67 Citations

Transport and proofreading of proteins by the twin-arginine translocation (Tat) system in bacteria

Robinson, C., Matos, C. F. R. O., Beck, D., Ren, C., Lawrence, J., Vasisht, N. & Mendel, S. Mar 2011 In : Biochimica et biophysica acta. 1808, 3, p. 876-884 9 p.

Research output: Contribution to journalArticle

Carrier Proteins
Protein Transport
Cell Membrane

Activities 2016 2019

  • 11 Public Engagement Event
  • 1 Participation in conference
  • 1 Invited talk
  • 1 Oral presentation

Chemistry for all

Williams, S. (Organiser)
18 Jan 20196 Apr 2019

Activity: Public Engagement Event

Chemistry week 2018

Williams, S. (Organiser)
23 Nov 201824 Nov 2018

Activity: Public Engagement Event

Chemistry for all

Williams, S. (Organiser)
29 Jun 201830 Jun 2018

Activity: Public Engagement Event

Chemistry for all

Williams, S. (Organiser)
27 Apr 201828 Apr 2018

Activity: Public Engagement Event


Coventry Excellence Awards

Igor Morozov (Recipient), Sharon Williams (Recipient), Jess Rollason (Recipient), Lauren Acton (Recipient) & Martin Cox (Recipient), 15 Jun 2015

Prize: Prize (including medals and awards)

Press / Media

Chemistry for all at the FabLab

Sharon Williams


1 media contribution

Press/Media: Public Engagement Activities

Chemistry week

Sharon Williams


1 media contribution

Press/Media: Public Engagement Activities

Introduction to DNA’ for primary pupils

Sharon Williams


1 media contribution

Press/Media: Public Engagement Activities