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Sharon Williams

Dr

    • Source: Scopus
    • Calculated based on no. of publications stored in Pure and citations from Scopus
    20012020

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    Personal profile

    Biography

    I have a PhD in Biochemistry. I worked as a post doctorate research fellow in both the Chemistry and the Biology departments of Warwick University between 2002 and 2010. My research focused on the biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes. I have a wide range and depth of research experience in molecular biology, biochemistry, and chemistry.

    I am member of the Royal Society of Chemistry and I am involved in many projects related to the society. I have joined Coventry University as a lecturer in November 2014 to continue my research into exploring enzymes mechanism in general and lignin degradation in particular.

    Area of Expertise:

    Biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes.

    Research Interests

    Enzymes mechanisms and protein structure

    Vision Statement

    I am very interested in applications for industrial biotechnology that could be developed and characterize novel bioproducts obtained by enzymatic oxidation of lignin. In addition, lignin degradation would release valuable low molecular weight aromatic chemicals that would add considerable value to biofuel production.

    My other interest is the twin-arginine translocation, or Tat pathway. In this pathway, substrates are synthesised with N-terminal signal peptides containing a key twin-arginine motif. The proteins are then transported by a membrane-bound Tat translocon which is uniquely able to transport fully folded proteins across the tightly coupled plasma membrane. One of the interests is how the system can be exploited for the production of high-value therapeutic proteins and also development of drug targets.

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