• 369 Citations
  • 9 h-Index
20012020

Research output per year

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Personal profile

Biography

I have a PhD in Biochemistry. I worked as a post doctorate research fellow in both the Chemistry and the Biology departments of Warwick University between 2002 and 2010. My research focused on the biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes. I have a wide range and depth of research experience in molecular biology, biochemistry, and chemistry.

I am member of the Royal Society of Chemistry and I am involved in many projects related to the society. I have joined Coventry University as a lecturer in November 2014 to continue my research into exploring enzymes mechanism in general and lignin degradation in particular.

Area of Expertise:

Biophysics and biochemistry of proteins, and understanding the mechanisms of enzymes.

Research Interests

Enzymes mechanisms and protein structure

Vision Statement

I am very interested in applications for industrial biotechnology that could be developed and characterize novel bioproducts obtained by enzymatic oxidation of lignin. In addition, lignin degradation would release valuable low molecular weight aromatic chemicals that would add considerable value to biofuel production.

My other interest is the twin-arginine translocation, or Tat pathway. In this pathway, substrates are synthesised with N-terminal signal peptides containing a key twin-arginine motif. The proteins are then transported by a membrane-bound Tat translocon which is uniquely able to transport fully folded proteins across the tightly coupled plasma membrane. One of the interests is how the system can be exploited for the production of high-value therapeutic proteins and also development of drug targets.

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Research Output

  • 369 Citations
  • 9 h-Index
  • 13 Article
  • 1 Commissioned report
  • 1 Review article

Detection of humic acid in water using flat-sheet and folded-rod viscous alkaline glucose syrups

Fakayode, O. J., Williams, S., Adekunle, A. S. & Thabo, N., 7 Apr 2020, In : Analyst. 145, 7, p. 2682-2691 10 p.

Research output: Contribution to journalArticle

  • Higher Education Outreach: Examining Key Challenges For Academics

    Johnson, M., Danvers, E., Hinton-Smith, T., Atkinson, K., Bowden, G., Foster, J., Garner, K., Garrud, P., Greaves, S., Harris, P., Hejmadi, M., Hill, D., Hughes, G., Jackson, L., O'Sullivan, A., O'Tuama, S., Brown, P. P., Philipson, P., Ravenscroft, S., Rhys, M. & 6 others, Ritchie, T., Talbot, J., Walker, D., Watson, J., Williams, M. & Williams, S., 2 Oct 2019, In : British Journal of Educational Studies. 67, 4, p. 469-491 23 p.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    Protein engineering of Pseudomonas fluorescens peroxidase Dyp1B for oxidation of phenolic and polymeric lignin substrates

    Pour, R. R., Ehibhatiomhan, A., Huang, Y., Ashley, B., Rashid, G., Mendel Williams, S. & Bugg, T. D. H., Apr 2019, In : Enzyme and Microbial Technology. 123, p. 21-29 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 3 Citations (Scopus)
    10 Downloads (Pure)

    Association for Academic Outreach Evidence Submission to the UPP Foundation Civic University Commission 2018 Association for Academic Outreach

    Williams, S., Talbot, J., Awesti, A., Bowden, G., Danvers, E., Foster, J. M., Hejmadi, M., Hinton-Smith, T., Lazarus, J., Melhuish, C., Moffat, C. R., O'Tuama, S., Walker, D., Watson, J. & Harris, N., 31 Jul 2018

    Research output: Book/ReportCommissioned report

    Expression of the bifunctional Bacillus subtilis TatAd protein in Escherichia coli reveals distinct TatA/B-family and TatB-specific domains

    Barnett, J. P., Lawrence, J., Mendel, S. & Robinson, C., Aug 2011, In : Archives of Microbiology. 193, 8, p. 583-594 12 p.

    Research output: Contribution to journalArticle

  • 10 Citations (Scopus)

    Activities

    Coventry University Group (Publisher)

    Sharon Williams (Associate Editor)
    25 Jun 2019

    Activity: Publication peer-review and editorial workPublication peer-review

    Chemistry for all interactive sessions

    Sharon Williams (Organiser)
    2 Sep 201930 Jun 2020

    Activity: Participating in or organising an eventPublic Engagement Event

    Chemistry for all

    Sharon Williams (Organiser)
    18 Jan 20196 Apr 2019

    Activity: Participating in or organising an eventPublic Engagement Event

    Introduction to the cell components and DNA fun activity for the family

    Sharon Williams (Organiser)
    22 Feb 201923 Feb 2019

    Activity: Participating in or organising an eventPublic Engagement Event

    Chemistry for all

    Sharon Williams (Organiser)
    27 Apr 201828 Apr 2018

    Activity: Participating in or organising an eventPublic Engagement Event

    Prizes

    Coventry Excellence Awards

    Igor Morozov (Recipient), Sharon Williams (Recipient), Jess Rollason (Recipient), Lauren Acton (Recipient) & Martin Cox (Recipient), 15 Jun 2015

    Prize: Prize (including medals and awards)

    Press / Media

    Chemistry for all at the FabLab

    Sharon Williams

    18/06/18

    1 Media contribution

    Press/Media: Public Engagement Activities

    Chemistry week

    Sharon Williams

    30/11/17

    1 Media contribution

    Press/Media: Public Engagement Activities

    Introduction to DNA’ for primary pupils

    Sharon Williams

    16/08/17

    1 Media contribution

    Press/Media: Public Engagement Activities