Projects per year
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Research Interests
My PhD research looked into the acute physiological response to exercise in end-stage renal disease with a specific focus on cardiac stunning during haemodialysis and potential of intra-dialytic exercise to reverse this effect. My current research has followed on from my PhD work looking into the causes of hypoxia during haemodialysis. I am also involved with the HIIT or MISS UK randomised control trial, investigating the effects of different intensities of exercise cardiac rehabilitation on cardiac structure and function using trans-thoracic echocardiogram. Our team is also looking into the effects of specific microRNAs that are responsible for cardioprotective with exercise cardiac rehabilitation to better justify cardiac rehabilitation for reducing pathological remodelling post-myocardial infarction.
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Projects
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EchoCOVID: Novel echocardiography methods to quantify cardiac structural and functional implications of Covid-19
Jakovljevic, D., Maddock, H., McGregor, G., McGuire, S. & Banerjee, P.
18/01/21 → 17/06/24
Project: Internally funded project
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pHHd: pH, Hypoxia and Haemodialysis
McGuire, S., McGregor, G., Horton, E., Jakovljevic, D. & Krishnan, N.
1/11/20 → 28/02/21
Project: Unfunded project
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PRECISE: Investigating the acute physiological response to exercise in end stage renal disease
McGregor, G., McGuire, S., Horton, E. & Renshaw, D.
3/10/16 → 31/03/20
Project: Internally funded project
Research output
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Cardiopulmonary and metabolic physiology during hemodialysis and inter-/intra-dialytic exercise
McGuire, S., Horton, E. J., Renshaw, D., Chan, K., Krishnan, N. & McGregor, G., 28 Jan 2021, In: Journal of Applied Physiology. (In-press), p. (In-press)Research output: Contribution to journal › Article › peer-review
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Ventilatory and chronotropic incompetence during incremental and constant load exercise in end-stage renal disease: a comparative physiology study
McGuire, S., Horton, E. J., Renshaw, D., Chan, K., Krishnan, N. & McGregor, G., 1 Sep 2020, In: American journal of physiology. Renal physiology. 319, 3, p. F515-F522 8 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Cardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise
McGuire, S., Horton, E. J., Renshaw, D., Chan, K., Jimenez, A., Maddock, H., Krishnan, N. & McGregor, G., 17 Dec 2019, In: CKJ: Clinical Kidney Journal. (In-Press), p. 1-10 10 p., sfz159.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design
Ali, D., Callan, N., Ennis, S., Powell, R., McGuire, S., McGregor, G., Weickert, M. O., Miller, M. A., Cappuccio, F. P. & Banerjee, P., 19 Nov 2019, In: BMJ Open. 9, 11, p. e027984 027984.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Hemodynamic Instability during Dialysis: The Potential Role of Intradialytic Exercise
McGuire, S., Horton, E. J., Renshaw, D., Jimenez, A., Krishnan, N. & McGregor, G., 27 Feb 2018, In: BioMed Research International. 2018, 11 p., 8276912.Research output: Contribution to journal › Review article › peer-review
Open AccessFile10 Citations (Scopus)111 Downloads (Pure)
Activities
- 1 Invited talk
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The therapeutic effect of intra-dialytic exercise
Scott McGuire (Speaker)
29 Oct 2020Activity: Talk or presentation › Invited talk
Thesis
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Acute Physiological Responses to ExerCISE in end-stage renal disease (PRECISE)
Author: McGuire, S., Apr 2020Supervisor: McGregor, G. (Supervisor), Horton, E. (Supervisor), Renshaw, D. (Supervisor) & Jimenez, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
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