Research output per year
Research output per year
Personal profile
Biography
Michael is a biochemist who studied Biochemistry at Bath University, during this time he spent time at the University of Michigan (USA) and Duke University (USA) for six-month placements. After his studies he worked for a year as a formulations technician at the vaccine company: PowderMed in Oxford. He returned to his studies for a DPhil (PhD) in the Department of Cardiovascular Medicine and the Department of Physiology, Anatomy and Genetics (DPAG) at the University of Oxford. His PhD work was on the application of novel magnetic resonance imaging and spectroscopy tools to better characterize metabolic alterations that occur during heart disease. Developing this further, he undertook a 2 year post-doc sponsored by the British Heart Foundation (BHF) to investigate the translation of his PhD work into human volunteers in the Oxford Centre for Clinical Magnetic Resonance Research. In 2014, Michael was awarded a Novo Nordisk Fellowship, to investigate the effects of fatty acids on the hearts ability to adapt to hypoxia.
Michael's research involves examining the metabolism of the failing and diseased heart. The healthy heart derives 60-80% of its energy from the burning of fat, the rest from carbohydrates and ketones. During heart disease this carefully balanced use of fuel can become breakdown. Understanding why this is the case and how to prevent the deterioration of this metabolic balance may provide clues on how to better treat heart disease.Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
DPhil, Doctorate, University of Oxford
1 Oct 2008 → 30 Sep 2012
Award Date: 22 Sep 2012
Biochemistry, MSc, University of Bath
1 Sep 2003 → 21 Jul 2007
Award Date: 21 Jul 2007
External positions
Committee Member: Education, Training and Outreach, Biochemical Society
1 Jan 2019 → …
Early Career Panel Member, Biochemical Society
1 Jan 2019 → …
Novo Nordisk Postdoctoral Fellow, University of Oxford
1 Oct 2014 → 31 Mar 2018
BHF Postdoctoral Researcher, University of Oxford
1 Oct 2012 → 30 Sep 2014
Keywords
- QP Physiology
- Metabolism
- Heart
- MRI
- Hypoxia
- Diabetes
- 3D Cell culture
- QH301 Biology
- Metabolism
- QM Human anatomy
- Heart
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Metabolism
Judge, A. & Dodd, M. S., 8 Oct 2020, In: Essays in Biochemistry. 64, 4, p. 607-647 41 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)44 Downloads (Pure) -
Fatty acids prevent Hypoxia-Inducible Factor 1α signalling in type 2 diabetes
Dodd, M., Sousa Fialho, M. D. L., Montes Aparico, C. N., Kerr, M., Timm, K. N., Griffin, J. L., Luiken, J. J. F. P., Glatz, J. F. C., Tyler, D. J. & Heather, L. C., Aug 2018, In: Journal of the American College of Cardiology: Basic to Translational Science. 3, 4, p. 485-498 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)66 Downloads (Pure) -
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI
Timm, K., Perera, C., Ball, V., Henry, J., Miller, J., Kerr, M., West, J., Sharma, E., Broxholme, J., Logan, A., Savic, D., Dodd, M., Griffin, J. L., Murphy, M., Heather, L. C. & Tyler, D. J., 19 Nov 2020, In: Communications Biology. 3, 10 p., 692 .Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)3 Downloads (Pure) -
Non-Invasive In Vivo Assessment of Cardiac Metabolism in the Healthy and Diabetic Human Heart Using Hyperpolarized 13C MRI
Rider, O., Apps, A., Miller, J., Lau, J., Lewis, A., Peterzan, M., Dodd, M., Lau, A., Trumper, C., Gallagher, F., Grist, J., Brindle, K., Neubauer, S. & Tyler, D. J., 13 Mar 2020, In: Circulation Research. 126, 6, p. 725-736 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)8 Downloads (Pure) -
The protective effects of GLP-1 and liraglutide on insulin resistant 3D kidney spheroids.
Judge, A., Thakore, J. & Dodd, M., 2019.Research output: Contribution to conference › Poster
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Acta Diabetologica (Journal)
Mike Dodd (Peer Reviewer)
Jun 2018Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of Cardiovascular Magnetic Resonance (Journal)
Mike Dodd (Peer Reviewer)
May 2018Activity: Publication peer-review and editorial work › Publication peer-review
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Acta Diabetologica (Journal)
Mike Dodd (Editorial Board Member)
2018 → …Activity: Publication peer-review and editorial work › Editorial activity
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Journal of Cardiovascular Magnetic Resonance (Journal)
Mike Dodd (Peer Reviewer)
Jul 2018Activity: Publication peer-review and editorial work › Publication peer-review