No photo of Jason Bennett
  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
20092019

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

Cancer immunotherapy has represented a paradigm shift in cancer therapy. However, at present immunotherapies help only a minority of patients and in certain types of cancer they are unsuccessful due to the overriding immunosuppression mechanisms in the tumour microenvironment (TME). The mechanisms underlying the immunoinhibitory activities of the TME are presently poorly understood. My research aims to apply various molecular biological techniques to discover novel non-enzymatic modulators of key pro-inflammatory signalling pathways. This could potentially identify and target key protein-protein interactions in order to release the “natural brakes” of inflammatory signalling pathways in innate immune cells. This research will advance our understanding of the regulatory mechanisms of innate immune cell signalling in the host’s response to pathogens and cancer leading to the development of a new class of innate immunotherapies, which will be able to convert immunological “cold” tumours (e.g. prostate, glioblastoma, ovarian and pancreatic cancer) into ones that are responsive to immunotherapy.

Education/Academic qualification

Post-doctoral Research Fellow, Imperial College London

1 Jan 201131 Dec 2018

PhD, Doctorate, University College Dublin

31 Oct 20041 Nov 2009

External positions

Honorary Research Fellow, Imperial College London

1 Jan 2019 → …

Keywords

  • RM Therapeutics. Pharmacology
  • Cancer Immunotherapy
  • Innate Immune Signalling
  • Tumor Microenvironment
  • Metabolism

Fingerprint

Dive into the research topics where Jason Bennett is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Network

Recent external collaboration on country level. Dive into details by clicking on the dots.
Your message has successfully been sent.
Your message was not sent due to an error.
If you made any changes in Pure these will be visible here soon.