Hoor Ayub

Dr

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    20202022

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    Biography

    Dr. Hoor Ayub is a research scientist within the Centre for Sports, Health and Life Sciences. She joined Coventry University in July 2019 as a postdoctoral researcher, working on membrane protein pharmacology and molecular biology. Hoor's current research is on understanding the structure, function and underlying molecular mechanism of G-protein coupled receptors (GPCRs) in the presence of receptor activity modifying proteins (RAMPs).  Hoor's work is  funded by BBSRC- industrial partnership award with Prof Mark Wheatley and in collaboration with Aston University, University of Birmingham and UCB biopharmaceutical company.

    Hoor completed her PhD in membrane protein biology and biotechnology from Aston University and in collaboration with Janssen, UK. Her PhD work gave rise to data on (i) stabilisation and purification of difficult to study membrane proteins in SMA co-polymers; (ii) novel biochemical, functional and structural data on tetraspanin family of membrane proteins; (iii) large-scale membrane protein production for X-ray crystallisation and cryo-electron microscopy studies. 

    Education/Academic qualification

    Biochemistry & Biotechnology, Doctorate, Membrane phospholipids as regulators of tetraspanin oligomerisation, Aston University

    8 Jul 201630 Jun 2019

    Award Date: 15 Jan 2020

    Molecular Biotechnology, MSc, University of Birmingham

    1 Sept 201430 Aug 2015

    Award Date: 15 Dec 2015

    External positions

    Health and Life Sciences Visiting Researcher, Aston University

    15 Jul 201930 Jun 2023

    Biosciences Visiting Researcher, University of Birmingham

    15 Jul 201930 Jun 2023

    Keywords

    • Q Science (General)
    • G-Protein-Coupled Receptors (GPCRs) Pharmacology
    • Biochemistry & Biotechnology
    • GPCR:RAMP interactions
    • Calcitonin Gene-Related Peptide Receptor
    • Receptor Activity Modifying Proteins
    • Family B GPCRs
    • Styrene Maleic Acid Lipid Particles
    • Nanobodies
    • Immunohistochemistry

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