Personal profile

Biography

Derek graduated with a PhD from the Department of Endocrinology at Bart's and The London School of Medicine and Dentistry, Queen Mary University of London in 2001. Since then he has completed post-doctoral posts within the University of London in areas including wound healing, appetite regulation and inflammation.

Derek works on models of inflammation and particularly the area of pro-resolution with a focus on Annexin A1 protein. He secured a lecturership in physiology at the University of Westminster in September 2007 and began to develop an independent academic research career. Derek continued to work in the area of inflammation and pursued a number of research areas including work on salivary biomarkers, the inflammation associated with adiposity and the use of anti-inflammatory substances as therapeutic agents.

Derek has also led a number of commercialization projects including a wound healing project investigating novel combinations of peptides in human tissue repair. Another externally funded project involved the development of a micro-particle based nutrient delivery platform for the oral delivery of iron. Derek was also Lead Academic of a Technology Strategy Board (now Innovate UK) funded Knowledge Transfer Partnership (KTP) grant between the University of Westminster and Nelsons Spatone®. In recognition of his achievements in the area of enterprise in January 2012 Derek was awarded the School of Life Sciences Entrepreneurial Prize Fellowship, which involved the co-ordination and academic leadership of all enterprise activities within the School of Life Sciences at the University of Westminster. Recently Derek joined the Centre for Applied Biological and Exercise Sciences at Coventry University as Professor of Translational Physiology and now provides academic leadership for the theme of Health and Disease within the research centre.

Area of Expertise:

Endocrinology/inflammation/gut physiology

Research Interests

Stress; Obesity; Satiety; Adipose tissue inflammation

Vision Statement

My research addresses a number of key areas of human health. My research led to the novel discovery that endogenous anti-inflammatory substances found in human blood are significantly attenuated in human obesity. This demonstrates the potential of using anti-inflammatory therapeutics to treat the inflammation associated with human obesity, a disease that is strongly linked with metabolic diseases such as type 2 diabetes. The overall aim of this research is to delineate the pathophysiological pathways, which link adipose tissue expansion to human disease in order to design pharmacological and life-style interventions to tackle this growing crisis in human metabolic disease.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Iron Medicine & Life Sciences
Hepcidins Medicine & Life Sciences
Hep G2 Cells Medicine & Life Sciences
Sulfates Medicine & Life Sciences
Chitosan Medicine & Life Sciences
In Vitro Techniques Medicine & Life Sciences
Palmitates Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1995 2017

Physical activity levels and barriers to exercise referral among patients with cancer

Yang, D. D., Hausien, O., Aqeel, M., Klonis, A., Foster, J. & Renshaw, D. 31 Jan 2017 In : Patient Education and Counseling. (in press)

Research output: Contribution to journalArticle

Motor Activity
Referral and Consultation
Exercise
Neoplasms
Time Perception
1 Citations

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells

Mehta, K., Busbridge, M., Renshaw, D., Evans, R. W., Farnaud, S. & Patel, V. B. Oct 2016 In : Blood Cells, Molecules, and Diseases. 61, p. 37-45 9 p.

Research output: Contribution to journalArticle

Open Access
File
Hepcidins
Hep G2 Cells
Iron
Messenger RNA
Iron Overload
1 Citations

Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells

Mehta, K., Greenwell, P., Renshaw, D., Busbridge, M., Garcia, M., Farnaud, S. & Patel, V. B. Aug 2015 In : Blood Cells, Molecules, and Diseases. 55, 2, p. 110–118 9 p.

Research output: Contribution to journalArticle

Hepcidins
Hep G2 Cells
Iron
Messenger RNA
Transferrin Receptors
2 Citations

Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: Preparation, characterisation and in vitro evaluation

Zariwala, M. G., Farnaud, S., Merchant, Z., Somavarapu, S. & Renshaw, D. 1 Mar 2014 In : Colloids and surfaces. B, Biointerfaces. 115, p. 86-92 7 p.

Research output: Contribution to journalArticle

Palmitates
Iron
In Vitro Techniques
iron
Ascorbyl palmitate
12 Citations

A novel approach to oral iron delivery using ferrous sulphate loaded solid lipid nanoparticles

Zariwala, M. G., Elsaid, N., Jackson, T. L., Corral López, F., Farnaud, S., Somavarapu, S. & Renshaw, D. 18 Nov 2013 In : Scientia pharmaceutica. 456, 2, p. 400-7 8 p.

Research output: Contribution to journalArticle

Nanoparticles
Sulfates
Iron
Lipids
Chitosan

Activities 2002 2014

  • 21 Participation in conference
  • 2 Participation in workshop, seminar, course

Society for Endocrinology BES 2014

Renshaw, D. (Speaker)
24 Mar 201427 Mar 2014

Activity: Participation in conference

European Iron Club meeting

Renshaw, D. (Speaker)
11 Sep 201414 Sep 2014

Activity: Participation in conference

Society for Endocrinology BES 2013

Renshaw, D. (Speaker)
18 Mar 201321 Mar 2013

Activity: Participation in conference

British Endocrine Societies annual conference

Renshaw, D. (Chair)
18 Mar 201321 Mar 2013

Activity: Participation in conference

British Endocrine Societies annual conference

Renshaw, D. (Co-chair)
18 Mar 201323 Mar 2013

Activity: Participation in conference