• 165 Citations
  • 6 h-Index
19952020

Research output per year

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Personal profile

Biography

Derek graduated with a PhD from the Department of Endocrinology at Bart's and The London School of Medicine and Dentistry, Queen Mary University of London in 2001. Since then he has completed post-doctoral posts within the University of London in areas including wound healing, appetite regulation and inflammation.

Derek works on models of inflammation and particularly the area of pro-resolution with a focus on Annexin A1 protein. He secured a lecturership in physiology at the University of Westminster in September 2007 and began to develop an independent academic research career. Derek continued to work in the area of inflammation and pursued a number of research areas including work on salivary biomarkers, the inflammation associated with adiposity and the use of anti-inflammatory substances as therapeutic agents.

Derek has also led a number of commercialization projects including a wound healing project investigating novel combinations of peptides in human tissue repair. Another externally funded project involved the development of a micro-particle based nutrient delivery platform for the oral delivery of iron. Derek was also Lead Academic of a Technology Strategy Board (now Innovate UK) funded Knowledge Transfer Partnership (KTP) grant between the University of Westminster and Nelsons Spatone®. In recognition of his achievements in the area of enterprise in January 2012 Derek was awarded the School of Life Sciences Entrepreneurial Prize Fellowship, which involved the co-ordination and academic leadership of all enterprise activities within the School of Life Sciences at the University of Westminster. Recently Derek joined the Centre for Applied Biological and Exercise Sciences at Coventry University as Professor of Translational Physiology and now provides academic leadership for the theme of Health and Disease within the research centre.

Area of Expertise:

Endocrinology/inflammation/gut physiology

Research Interests

Stress; Obesity; Satiety; Adipose tissue inflammation

Vision Statement

My research addresses a number of key areas of human health. My research led to the novel discovery that endogenous anti-inflammatory substances found in human blood are significantly attenuated in human obesity. This demonstrates the potential of using anti-inflammatory therapeutics to treat the inflammation associated with human obesity, a disease that is strongly linked with metabolic diseases such as type 2 diabetes. The overall aim of this research is to delineate the pathophysiological pathways, which link adipose tissue expansion to human disease in order to design pharmacological and life-style interventions to tackle this growing crisis in human metabolic disease.

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Projects

Research Output

  • 165 Citations
  • 6 h-Index
  • 13 Article
  • 3 Review article
  • 2 Poster
  • 1 Abstract

Age-related degeneration of the lumbar paravertebral muscles: Systematic review and three-level meta-regression

Dallaway, A. D. F., Kite, C., Griffen, C., Duncan, M., Tallis, J., Renshaw, D. & Hattersley, J., 30 Jan 2020, In : Experimental Gerontology. 133, 110856.

Research output: Contribution to journalReview article

  • Cardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise

    McGuire, S., Horton, E. J., Renshaw, D., Chan, K., Jimenez, A., Maddock, H., Krishnan, N. & McGregor, G., 17 Dec 2019, In : CKJ: Clinical Kidney Journal. (In-Press), 10 p., sfz159.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Downloads (Pure)

    Tiotropium bromide, a long acting muscarinic receptor antagonist triggers intracellular calcium signalling in the heart

    Cassambai, S., Mee, C. J., Renshaw, D. & Hussain, A., 1 Dec 2019, In : Toxicology and Applied Pharmacology. 384, 114778.

    Research output: Contribution to journalArticle

  • Hemodynamic Instability during Dialysis: The Potential Role of Intradialytic Exercise

    McGuire, S., Horton, E. J., Renshaw, D., Jimenez, A., Krishnan, N. & McGregor, G., 27 Feb 2018, In : BioMed Research International. 2018, p. 8276912 11 p., 8276912.

    Research output: Contribution to journalReview article

    Open Access
    File
  • 5 Citations (Scopus)
    87 Downloads (Pure)

    Activities

    • 21 Participation in conference
    • 2 Participation in workshop, seminar, course

    European Iron Club meeting

    Derek Renshaw (Speaker)
    11 Sep 201414 Sep 2014

    Activity: Participating in or organising an eventParticipation in conference

    Society for Endocrinology BES 2014

    Derek Renshaw (Speaker)
    24 Mar 201427 Mar 2014

    Activity: Participating in or organising an eventParticipation in conference

    Society for Endocrinology BES 2013

    Derek Renshaw (Speaker)
    18 Mar 201321 Mar 2013

    Activity: Participating in or organising an eventParticipation in conference

    British Endocrine Societies annual conference

    Derek Renshaw (Co-chair)
    18 Mar 201323 Mar 2013

    Activity: Participating in or organising an eventParticipation in conference

    British Endocrine Societies annual conference

    Derek Renshaw (Chair)
    18 Mar 201321 Mar 2013

    Activity: Participating in or organising an eventParticipation in conference