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20192022

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Personal profile

Research Interests

Ahmed Elwakeel is a pharmacist who has been awarded a bachelor’s degree in Pharmaceutical Sciences at Alexandria University, Egypt. He embarked on his research career at the Biotechnology Department of the Institute of Graduate Studies and Research (IGSR) of Alexandria University through undertaking pre-masters level-graduate studies. Then, leading his research colleagues at the City for Scientific Research and Technology Applications (SRTA-City), Alexandria, he utilized the in vitro triple-negative breast cancer model (MDA-MB-231 cells) to examine the single and combined cytotoxicity of PU-H71, Dehydroepiandrosterone, Berberine, and Sorafenib to define and quantify the in vitro pharmacodynamic interactions of their combinations (synergism, antagonism, or additivity) based on Median Effect Equation (Chou), Combination Index Theorem and Dose Reduction Index Equation (Chou-Talalay). He is currently invited as an oral presenter at the Synergy Forum that will be held on the 13th and 14th of May 2023 in Bonn, Germany.

 

In 2018, Ahmed was accepted as a participant in the prestigious Master’s Degree and Internship program of the African Business Education (ABE) Initiative by the Japan International Co-operation Agency (JICA) to study the molecular mechanism of diseases at the School of Integrative and Global Majors (SIGMA) at Tsukuba University, Japan. Under the supervision of Renu Wadhwa at the National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba campus, he identified MortaparibPlus as a novel synthetic small molecule possessing the potentiality to abrogate mortalin-p53 interaction and characterized its cytotoxic and molecular effects on Luminal-A breast cancer and colorectal cancer in vitro models.

 

In 2021, Ahmed has been accepted into the PhD studentship program at Coventry University under the ‘’Trailblazers: The Early-Career Researcher and Doctoral Studentship Partnering Scheme’’ from 18th January 2021 to 31st July 2024. As a Post Graduate Researcher (PGR) at the Center for Sports, Exercise and Life Science (CSELS) of Coventry University, he is currently utilizing in vitro dendritic cell models to investigate the mechanistic role of Gadd45b as an NF-kB-regulated protein in dendritic cell activation and migration processes.

 

Ahmed has been trained as a cellular and molecular biologist with extensive technical expertise in cell-based and molecular biology-based research methodologies, for instance, anchorage-dependent cancer cell culture techniques, cytotoxicity analyses, gene expression analyses, immunoprecipitation, immunocytochemistry, luciferase reporter assays, apoptosis detection and cell cycle analyses, lipid-based transfection of mammalian cells and others.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 1 - No Poverty
  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 6 - Clean Water and Sanitation
  • SDG 16 - Peace, Justice and Strong Institutions

Education/Academic qualification

Life Science Innovation, Disease Mechanism , MSc, University of Tsukuba

20182020

Award Date: 5 Oct 2020

Biotechnology, Postgraduate Certificate, Alexandria University

Award Date: 4 Jun 2018

Pharmaceutical Sciences, Degree, Alexandria University

20072012

Award Date: 29 Jun 2012

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