A fractional order model of the cardiac function

Activity: Talk or presentationOral presentation


In 2015, 17.9 million people died around the world caused by a cardiovascular disease and rose by 12.5% between 2005 and 2015 with a specific increase of ischemic heart disease by 16.6%. Even though heart transplantation is considered as the best therapy for patients with end-stage congestive heart failure, it is usually a delayed process that could last around 300 days or more on the average for potential recipients. For this reason, the medical community has increased emphasis on the use of ventricular assist devices that can enhance the function of the natural heart while patients wait for a heart transplantation. The use of such devices implies a need for an accurate mathematical model that facilitates the use of optimal control techniques. To address this issue, this work explores the use of Fractional Calculus in a nonlinear mathematical model which consistently solves the myocyte contraction, electric activity and ventricle pressure-volume relation at the organ level at the same time over multiple cardiac cycles. In particular, we study the effect of fractional-order operators on chaotic dynamics (e.g. arrhythmia) in the cardiovascular system
Period23 Oct 2020
Event titleChaotic Modeling & Simulation Web Conference
Event typeConference
Degree of RecognitionInternational